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Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 46 / No. 3 / Published : 2013-09

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Original Article :

The role of calcium on enamel hypoplasia prevention

Author :

  1. Soegeng Wahluyo*1
  1. Dosen Fakultas Kedokteran Gigi

Abstract :

Background: Fluoride is a trace element found in many natural and commonly consumed by humans in the form of fluoride salts such as Sodium Fluoride (NaF). The impacts that are most often caused by the intake of fluoride is a damage of enamel tooth/enamel hypoplasi or fluorosis. The manifestations of these effects are defects in teeth with whitish colour, brown to black colour effected on the aesthetic. So that the alternative required prevention of fluorosis. Purpose: The aim of this study was to analyze the effect of calcium as prevention against tooth enamel fluorosis in Wistar rats caused by exposure to fluoride through indicators Amelogenin, Calbindin-28kDa protein expression, the matrix of tooth enamel density and distance between ameloblast cell. Methods: This is an experimental studies, post-test only control group design. This study uses three groups of rats. Group 1 (Control) was induced by sterile destilled water, group 2 (treatment 1) was induced by fluoride ang group 3 (treatment 2) was induced by combination of fluoride and calcium. Each induction is through sonde for 28 days. Results: The results showed that the induction of fluoride causes the increased expression of Amelogenin protein and decreased expression of Calbindin-28kDa protein and a decrease in the density of the enamel matrix and widen the distance between cells ameloblast, while the result of the combination induced by fluoride and calcium showed increased protein expression of Calbindin-28kDa and increased density of the enamel matrix. Conclusion: Calcium can be used as an alternative preventive against the occurrence of enamel hypoplasi due to exposure of fluoride in Wistar rats.

Keyword :

Fluorosis, calcium, amelogenin, calbindin-28kDa, enamel matrix density,


References :

Catani DB,(2010) Fluorosis in rats exposed to oscillating chronic fluoride doses - : Braz Dent





Archive Article

Cover Media Content

Volume : 46 / No. : 3 / Pub. : 2013-09
  1. Correlation Between Salivary Leptin Levels And Incidence Of Caries In Obese Children
  2. The Role Of Calcium On Enamel Hypoplasia Prevention
  3. The Correlation Of Micronucleus Formation And 8-oxo-dg Expression Due To The Panoramic Radiography Exposure
  4. Fluoride Determination Of Children And Adult Toothpaste By Spectrophotometry
  5. Heteroplasmy Analysis Of Dental Pulp Mitochondrial Dna In Forensic Personal Identification
  6. Effect Of Gestational Diabetes Mellitus On The Expression Of Amelogenin In Rat Offspring Tooth Germ
  7. The Effect Of Chitosan Gel Concentration To Neutrophyl And Macrophage In Gingival Ulcer
  8. Epstein-barr Virus (ebv) Dna As Biomaker Of Nasopharyngeal Carcinoma Diagnosis
  9. Metal Crown Restoration With Fiber Post In Young First Permanent Molar
  10. Cranial Size And Cephalic On Index Mentally Retarded 7–12 Years Old Children
  11. Mechanism Of Pomegranate Extract In Killing Malignant Cells In Mice Through Oral Cavity Mucosa Increased Expression Of P53 Wild

Information DENTJ