UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 41 / No. 1 / Published : 2008-01

Related with : Scholar   Yahoo!   Bing

Original Article :

The role of transforming growth factor beta in tertiary dentinogenesis

Author :

  1. Tetiana Haniastuti*1
  2. Phides Nunez*2
  3. Ariadna A. Djais*3
  1. Oral Biology Department, Gadjah Mada University, Indonesia
  2. Division of Oral Ecology in Health and Infection, Niigata University, Japan
  3. Oral Biology Department, University of Indonesia, Indonesia

Abstract :

The most visible repair response to pulp injury is the deposition of a tertiary dentin matrix over the dentinal tubules of the primary or secondary dentin. Tertiary dentin is distinguished as reactionary and reparative dentin, depending on the severity of the initiating response and the conditions under which the newly deposited dentin matrix was elaborated. Transforming growth factor beta (TGF-) superfamily is a large group of growth factors that serve important roles in regulating cell growth, differentiation, and function. Members of this superfamily have been implicated in the repair process of the dental tissue after injury. Although numerous studies have proved that those bioactive molecules carry out an important role in the formation of tertiary dentin, comprehensive report regarding that phenomenon is not yet available. This review article aimed to summarize the role of TGF- on tertiary dentinogenesis during the progression of a carious lesion.

Keyword :

transforming growth factor beta, tertiary dentinogenesis, reactionary dentin, reparative dentin,


References :

Mitsiadis,(2004) Parallels between tooth development and repair: conserved molecular mechanisms following carious and dental injury - : Journal Dental Restoration

Rahiotis,(2004) Parallels between tooth development and repair: conserved molecular mechanisms following carious and dental injury - : Journal Dental Restoration

Smith,(1995) Reactionary dentinogenesis - : Int J Dev Biol

Cassidy,(1995) Reactionary dentinogenesis - : Int J Dev Biol

Perry,(1995) Reactionary dentinogenesis - : Int J Dev Biol

Begue Kirn,(1995) Reactionary dentinogenesis - : Int J Dev Biol

Ruch,(1995) Reactionary dentinogenesis - : Int J Dev Biol

Lesot,(1995) Reactionary dentinogenesis - : Int J Dev Biol

Cohen,(2002) Pathway of the pulp St Louis : Mosby

Burns,(2002) Pathway of the pulp St Louis : Mosby

Klinge,(1999) A microradiographic and electron microscopic study of tertiary dentin in human deciduous teeth - : Acta Odontol Scand

St



Archive Article

Cover Media Content

Volume : 41 / No. : 1 / Pub. : 2008-03
  1. Three Dimensional Changes In Maxillary Complete Dentures Immersed In Water For Seven Days After Polymerization
  2. The In Vitro Assessment Of Anti Proliferation Activity Of Crude Diethyl Ether Extract Of Dendrophthoe Species To Myeloma Culture Cell
  3. Coen’s Ascending Ramus Fixator Use For Repositioning The Ascending Ramus During Mandible Reconstruction
  4. The Role Of Transforming Growth Factor Beta In Tertiary Dentinogenesis
  5. Morphological Changes Of Alveolar Bone Due To Orthodontic Movement Of Maxillary And Mandibulary Incisors
  6. The Effect Of Psidium Guajava Linn Leaf Extract On Candida Albicans Adherence And The Transversal Strength Of Acrylic Resin
  7. Side Effects Of Mercury In Dental Amalgam
  8. Pulp Tissue Vacuolization And Necrosis After Direct Pulp Capping With Calcium Hydroxide And Transforming Growth Factor-1
  9. Antimicrobial Effect Of Calcium Hydroxide As Endo Intracanal Dressing On Streptococcus Viridans
  10. Gingival Immunologic Defense Index: A New Indicator For Evaluating Dental Plaque Infection Risk In Allergic Children
  11. Expression Toll-like Receptors In The Oral Mucosal Of Patients With Recurrent Aphthous Stomatitis

Information DENTJ