UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 43 / No. 1 / Published : 2010-03

Order : 3, and page :11 - 16

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Original Article :

Tissue engineered bone as an alternative for repairing of bone defects

Author :

  1. Evy Eida Vitria*1
  2. Benny S. Latif*2
  1. Department of Oral & Maxillofacial Surgery
    Faculty of Dentistry, Universitas Indonesia
    Jakarta – Indonesia
  2. Department of Oral & Maxillofacial Surgery
    Faculty of Dentistry, Universitas Indonesia
    Jakarta – Indonesia

Abstract :

Background: Dentist especially oral surgeon, are frequently faced with defect in bone resulting from disease or trauma. If the defect is small, it will frequently has a good healing, however, if the defect is larger, incomplete regeneration often occurs and a fibrous scar results. Transplantation of autogenous bone has been one of the most frequent procedures of reconstructive oral and maxillofacial surgery because it has shown excellent clinical success; however, autogenous bone grafting is often related to disadvantages like limited availability, and donor morbidity. Purpose: The purpose of this review is to explain the basic principles of tissue engineering, background of regeneration process, also advantages and disadvantages of tissue engineered bone compared to autogenous bone graft. Review: Recently, using tissue engineered bone provides a promising strategic innovation and a new alternative for bone regeneration process. Tissue engineering is a term originally used to describe tissue produced in isolation and culture by cells seeded in various porous absorbable matrices. Tissue engineering generally combines three key elements (Tissue Engineering Triad) i.e: Scaffolds (matrices), signaling molecules (growth factors), and cells (osteoblast, fibroblast, etc). Conclusion: Tissue engineering will facilitate initial bone healing in order to accomplish tissue regeneration process.

Keyword :

Tissue engineering, autogenous bone graft, transplantation,


References :

Lynch SE,(1999) Tissue engineering: Applications in maxillofacial surgery and periodontics Illinois : Quintessence Publishing Co





Archive Article

Cover Media Content

Volume : 43 / No. : 1 / Pub. : 2010-03
  1. The Comparison Between Minocycline Oral-rinse And Gel On Pocket Depth
  2. The Frequency Of Bottle-feeding As Main Factor In Baby Bottle Tooth Decay Syndrome
  3. Relationship Between Trauma Mechanism And Etiology On Mandibular Fracture Patterns
  4. Noma Management In A Child With Systemic Lupus Erythematosus
  5. Tissue Engineered Bone As An Alternative For Repairing Of Bone Defects
  6. Mozart Effect On Dental Anxiety In 6-12 Year-old Children
  7. The Comparison Of Minocycline Oral Rinse And Gel To Reduce Pocket Depth
  8. Human-leukocyte Antigen Typing In Javanese Patients With Recurrent Aphthous Stomatitis
  9. Mengkudu (morinda Citrifolia Linn.) Gel Effect On Post-extraction Fibroblast Acceleration
  10. Special Considerations For Orthodontic Treatment In Patients With Root Resorption
  11. Various Curing Methods On Transverse Strength Of Acrylic Resin
  12. The Frequency Of Bottle Feeding As The Main Factor Of Baby Bottle Tooth Decay Syndrome

Information DENTJ