UNIVERSITAS AIRLANGGA



Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 47 / No. 2 / Published : 2014-06

Order : 10, and page :110 - 114

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Original Article :

Topical applications effect of casein phospho peptide-amorphous calcium phosphate and sodium fluoride on salivary mutans streptococci in children

Author :

  1. Fajriani*1
  2. Aini Dwi Handini*2
  1. Department of Pediatric Dentistry Faculty of Dentistry, Universitas Hasanuddin, Makassar – Indonesia
  2. Department of Pediatric Dentistry Faculty of Dentistry, Universitas Hasanuddin, Makassar – Indonesia

Abstract :

Background: Dental caries is one of the major human diseases caused by Mutans Streptococci (MS). Topical application casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) dan Sodium fluoride are often use in children and play a role in the caries prevention. Purpose: The aim of study was to determine the effect of casein phosphopeptide–amorphous calcium phosphate (CPP-ACP) and Sodium fluoride topical applications to the number of salivary MS colonies in children. Methods: This study using cross-over design with quase experiment time-series. The subjects were 30 children in range of age 6-12 years old that obtained with simple random sampling. The saliva samples of subjects were collected 3 times. First, saliva samples were taken before the treatment; second, after CPP-ACP topical application; third, after sodium fluoride topical application. Between the CPP-ACP and sodium fluoride treatments there was a one week wash-out period. After each treatment, saliva samples were taken twice, 15 and 30 minutes after topical applications respectively. After cultivation on specific agar, the colony number of salivary MS was determined by colony counting (Colony Forming Units-CFU). Results: There was no significant difference between topical application casein phosphopeptide – amorphous calcium phosphate (CPP-ACP) and Sodium fluoride in reducing the number of Streptococcus mutans. But topical application of Sodium fluoride tended to show more reduction than CPP-ACP. Conclusion: The topical application of CPP-ACP and Sodium fluoride could reduce the number of salivary MS in children. The effect of Sodium Fluoride was somewhat greater than CPP-ACP.  

Keyword :

Casein phosphopeptide–amorphous calcium phosphate, sodium fluoride, Streptococcus mutans, saliva, children,


References :

Ravinshankar TL ,(2012) Effect of consuming different dairy products on calcium, phosphorus and pH levels of human dental plaque; a comparative study - : Eur Arc of Ped Dent





Archive Article

Cover Media Content

Volume : 47 / No. : 2 / Pub. : 2014-06
  1. Characteristic Evaluation Of Rice Husk Ash With Chitosan High Molecule Nanoparticle As Dentinogenesis Material
  2. The Relationship Determination Between Menarche And The Peak Of Skeletal Maturation Using Hand Wrist And Cervical Vertebrae Inde
  3. The Maturition And Eruption Of Permanent Teeth In Mixed Dentition Children
  4. Surgical Exposure And Orthodontic Treatment On Labially Impacted Maxillary Central Incisor
  5. Reduction Of Salivary Mutans Streptococci In Children With Fixed Orthodontic Appliance After Yoghurt Consumption
  6. Application Of Social Learning Theory In The Management Of Children Dental Fear And Anxiety
  7. Correcting Occlusal Vertical Dimension Using Modified Stainless Steel Crown Restoration In Severe-early-childhood-caries Case
  8. Correction Of Posterior And Anterior Crossbite Using Fixed Orthodontic Appliance With Rapid Maxillary Expansion And Intermaxillary Elastic
  9. Iron Exposure To Specific Protein Expression Of Extracellular Polymeric Substance (eps) Of Aggregatibacter Actinomycetemcomitans Biofilm
  10. Topical Applications Effect Of Casein Phospho Peptide-amorphous Calcium Phosphate And Sodium Fluoride On Salivary Mutans Streptococci In Children
  11. The Characterization Of Stem Cells From Human Exfoliated Deciduous Teeth Using Trypsin Enzym

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