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Detail Article

Dental Journal (Majalah Kedokteran Gigi)

ISSN 1978-3728

Vol. 42 / No. 3 / Published : 2009-07

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Original Article :

Treatment of recurrent aphthous stomatitis major with metronidazole and ciprofloxacin

Author :

  1. M. Jusri*1
  2. Nurdiana*2
  1. Department of Oral Medicine
    Faculty of Dentistry, Airlangga University
    Surabaya - Indonesia
  2. Resident of Oral Medicine
    Faculty of Dentistry, Airlangga University
    Surabaya - Indonesia

Abstract :

Background: Recurrent aphthous stomatitis (RAS) are painful oral ulcerations that recur from days to months or even years. It represents the most common lesion of the oral mucosa with prevalence ranging from 15% to 30%. Although the clinical characteristics of RAS are well defined, the precise etiopathogenesis of RAS remains unclear. Since the etiology of RAS remains unknown, there is no definitive treatment. RAS responds quite well to the use of topical or systemic antiinflammatory drugs, particularly corticosteroids. Purpose: The objective of this paper is to discuss the treatment of RAS with secondary infection. Case: This paper reported a case of 22-year-old man with multiple oral ulcers that did not heal for 7 months. Case Management: These ulcers were diagnosed as RAS major with secondary infection that caused by normal oral flora (aerobic and anaerobic bacteria) and treated with metronidazole (topical and oral) and ciprofloxacin (oral). These lesions healed in 3 weeks with scars. Conclusion: Large ulcer without signs of malignancy that contaminated with normal oral flora will delayed in healing, but with rational treatment RAS mayor with secondary infection has good prognosis.

Keyword :

recurrent aphthous stomatitis, major ulcer, metronidazole, ciprofloxacin,

References :


    Archive Article

    Cover Media Content

    Volume : 42 / No. : 3 / Pub. : 2009-09
    1. Treatment Of Recurrent Aphthous Stomatitis Major With Metronidazole And Ciprofloxacin
    2. Mechanical Properties Of Carving Wax With Various Ca-bentonite Filler Composition
    3. Immunoglobulin-g Level On Aggressive Periodontitis Patients Treated With Clindamycin
    4. Color Stability Of Visible Light Cured Composite Resin After Soft Drink Immersion
    5. Storage Duration Effect On Deformation Recovery Of Repacked Alginates
    6. The Influence Of Xylitol Containing Toothpaste On Plaque Formation Inhibition On Fixed Bridge
    7. Functional Relationship Of Room Temperature And Setting Time Of Alginate Impression Material
    8. The Role Of  Msx1 And Pax9 In Pathogenetic Mechanisms Of  Tooth Agenesis
    9. The Use Of Holmium-yttrium Aluminum Garnet Laser As Pit And Fissure Cleaner