UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 35 / No. 4 / Published : 1999-10

Related with : Scholar   Yahoo!   Bing

Original Article :

Acute toxicity studies of ganoderma lucidum

Author :

      Abstract :

      Studies on acute toxicity of Ganoderma lucidum from fruit body, mycelium, or mixture (ratio 220 : 450) were done. Ganoderma lucidum powder has dry weight of 1 : 20 of its wet weight. The objective of this study was to determine LD50 of Ganoderma lucidum in albino wistar rat, guinea pig, and mongrel dog, from which the result was converted to that of rat to match the toxicity classification of AIHA (American Industrial Hygiene Association). This study demonstrated that Ganoderma lucidum fruit body powder was classified to be practically non toxic (LD50 > 5 g/kgBW), and so was the mixture of Ganoderma lucidum fruit body and mycelium powder, while Ganoderma lucidum mycelium powder was classified to be relatively harmless (LD50 > 15 g/kgBW).

      Keyword :

      Acute toxicity, LD50, Ganoderma lucidum, Ling zhi, Reishi,


      References :





      Archive Article

      Cover Media Content

      Volume : 35 / No. : 4 / Pub. : 1999-10
      1. Improving The Formulae To Calculate Genetic Variations In Sexually Reproducing Organisms
      2. Analgesia In Kidney Stone Treatment With Extracorporeal Piezoelectric Lithotripsy (epl): A Comparative Study
      3. Pharmacokinetic Of The New Macrolide Antibiotics: Azithromycin, Clarithromycin, Dirithromycin, And Roxithromycin
      4. Acute Toxicity Studies Of Ganoderma Lucidum
      5. Synaptic Regulation Of Adrenergic Activity And Micturition
      6. Ace-inhibitors,beneficial Action For Organ Protection And New Aspects Of Clinical Usefulness
      7. Prospective Observation On Influential Factors Of Puerperal Febrile Incidence In Keruak Subdistrict, District Of East Lombok, West Nusa Tenggara
      8. A Successful Surgical Repair Of An Impending Rupture Of Lv Aneurysm, Combined With Septal Perforation (vsd) And Rupture Of Papillary Muscle (mild Mitral Regurgitation) After Acute Myocardial Infarction
      9. Morphology And Distribution Of Mnng Induced Colon Tumors In The Wistar Rats
      10. Development Of Child Growth Curves Of Elementary School Children
      11. Quality Improvement Program In Residency Training, The Role Of Clinical Epidemiology

      Information FMI