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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 48 / No. 4 / Published : 2012-10

TOC : 1, and page :144 - 149

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Original Article :

Antibacterial activity of belimbing wuluh (averrhoa bilimbi linn) extract on salmonella typhi growth

Author :

  1. Fitria Hasdiana*1
  2. Sutji Kuswarini*2
  3. Eko Budi Koendhari*3
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Typhoid fever is an endemic disease which still have high incidence rate especially in developing countries like Indonesia. Typhoid fever is caused by Salmonella typhi. Starfruit (Averrhoa bilimbi Linn) leaf extract has antibacterial capability against some strains of bacteria. Therefore, researchers examined the use of starfruit leaf extract against Salmonella thypi bacteria. This was a true experimental research that test the antibacterial activity of the starfruit (Averrhoa bilimbi Linn) leaf extract against Salmonella typhi growth. This research using diffusion method on Muller Hinton Agar Palte. Starfruit leaf extracted with ethanol and divided in several concentrations. Statistical tests is conducted with descriptive test and Kruskal Wallis test to compare antibacterial effect of starfruit leaf extract in different concentrations in Salmonella thypi. Mean diameter of the inhibition on Salmonella typhi antibacterial activity test were as follows : Treatment 1 (0.3 g/ml) = 20.75 mm; Treatment 2 (0.4 g/ml) = 21.88 mm; Treatment 3 (0, 5 g/ml) = 22.88 mm; Control 1 (chloramphenicol 30 mcg) = 30 mm; Control 2 (5% DMSO) = 0 mm. Based on the obtained results, qualitatively it can be concluded that the concentration of starfruit (Averrhoa bilimbi Linn) leaf extract gave growth inhibition zone in Salmonella typhi at concentrations of 0.3 g/ml, 0.4 g/ml and 0.5 g/ml. Based on the standard Clinical Laboratory Standard Institute (2008), all of them provide a sensitive response to inhibit the growth of Salmonella typhi as well as giving antibiotic chloramphenicol as control. (FMI 2012;48:144-149)

Keyword :

Salmonella typhi, Averrhoa bilimbi Linn leaf, antibacterial, diffusion,


References :

  1. Robinson T, (1991). The Organic Constituents of High Plant, 4th ed . New York : University of Massachusetts
  2. Sampurno, (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat . Jakarta : Departemen Kesehatan


   


Archive Article

Cover Media Content

Volume : 48 / No. : 4 / Pub. : 2012-10
  1. Antibacterial activity of belimbing wuluh (averrhoa bilimbi linn) extract on salmonella typhi growth
  2. Oral and topical aloe vera extract administration in diabetic mice (mus musculus) wound healing process
  3. Effect of combined 500 mg vitamin c and 200 iu vitamin e on plasma malondialdehyde level after physical exercise in diving athletes
  4. Antibacterial activity of kunyit (curcuma longa) leaves extract on staphylococcus aureus examined using dilution method
  5. Antibacterial effect of strawberry (fragaria x ananassa) extract on pathogenic serotype 1-11 escherichia coli revealed using dilution method
  6. Guava (psidium guajava l.) juice is effective in lowering blood glucose level in mice (mus musculus)
  7. Clinical profile of children with steroid-sensitive idiopathic nephrotic syndrome relapsing in the first year at dr. soetomo hospital, surabaya
  8. The effects of soot particulate exposure on tnf-α expression in the mechanism of cardiovascular disorders
  9. Atomoxetine therapy effectiveness in children with adhd at day care, dr. soetomo hospital, surabaya
  10. Sweet star fruit reduces blood pressure in normotensive subjects