UNIVERSITAS AIRLANGGA



Detail Article

Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 4 / No. 2 / Published : 2015-12

Order : 9, and page :131 - 135

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Original Article :

Antibacterial activity of phyllanthus niruri l extract as substitute alternative flumequin antibiotic to e. coli on broiler

Author :

  1. Lalu Aditya Pratama Putra*1
  2. Soeharsono*2
  3. Sri Chusniati*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

Alkaloid, saponin dan tanin which are concentrated in the extract of Phyllanthus niruri L are widely known to have antibacterial activity. The aim of this research was to know antibacterial activity of Phyllanthus niruri L extract with flumequin antibiotic to E. coli on broiler by isolation and identification from the sample of hepar tissue. In this research, broiler at the age of twenty eight days were divided into six groups. All groups except control negative group were infected by E. coli dose 106 CFU/ml. Three groups were positive control, negative control, flumequin antibiotic control. The next three groups  were extract of Phyllanthus niruri L that were variated in three dosages: 20%, 25% and 30%. The treatment was given one day after infected E. coli. Pengobatan dilakukan sehari setelah diinfeksi E. coli. After five days treatment the broiler was necropted to take the sample of hepar tissue. The data were tested with Chi-Square Test. There was a significant difference of antibacterial activity beetwen control positive group (P0 +), treatment group dose 30% (P 3) and flumequin antibiotic (P Ab). The result showed that antibacterial activity of P3 had the same as with flumequin antibiotic to E. coli.  The conclusion was Phyllanthus niruri L extract can be used as substitute alternative antibacterial to E. coli  

Keyword :

Phyllanthus niruri L, antibacterial, E. coli, , broiler,


References :

Hooper and Wolfson. . ,(1985) The Fluoro-quinolones: Structure, Mecha¬nisms of Action and Resistance and Spectra of Activity in Vitro. 28: 581-586 : Antimicrob Agents Chemo¬therap

Karlina, C. K., Ibrahim, M., Trimulyono, G. ,(2013) Aktivitas Antibakteri Ekstrak Herba Krokot (Porlulaca oleracea L.) Terhadap Staphylo¬coccus aureus dan Escherichia coli. Vol. 2(1): 87-93 : Lentera Bio.

Soni, K. . ,(2012) Fluoroquinolones: Chemis¬ try & Action–A Review. Indo Glo¬bal Vol. 2(1): 43-53 : Journal Of Pharma-ceutical Sciences.





Archive Article

Cover Media Content

Volume : 4 / No. : 2 / Pub. : 2015-12
  1. The Effect Of Giving Vitamin C On Endosulfan Induced In Histopathologic Liver Of Mice (mus Musculus)
  2. Influence Of Hibiscus Sabdariffa L. Calyx On Alveolar Histopathological Feature Of Cigarette Smoke Exposed Mice
  3. The Effect Of L-arginine Orally On The The Histologycal Of Seminiferous Tubules Of Rabbit (oryctolagus Cuniculus) Testicular
  4. Infusum Cincau Green Leaves As The Use Inflammatory Gastric On White Rat (rattus Norvegicus ) Induced Use Caffeine With Inspection Histopathology
  5. The Influence Of Sambiloto Leaf (andrographis Paniculata) Extract As An Imunostimulator Against The Proliferation Of Lymphocyte
  6. Effects Of Plant Wood Yellow Leaf Extract (arcangelisia Flava Merr) As To Prevent Hepatic Dysfunction Examination Levels Of Bilirubin, Sgot Sgpt And Serum Blood On White Rat (rattus Norvegicus)
  7. Activitiy Test Of Snail Mucus (achatina Fulica) On The Healing Level Of Incision Wound Grossly And Microscopically In Batik Python Snake (python Reticulatus)
  8. Prevalence And Degree Of Gastrointestinal Helminth Infections In Cervus Timorensis (blainville 1822) (timor Deer) And Axis-axis (exrl 1788) (axis Deer) In The Pendopo Tulungagung
  9. Antibacterial Activity Of Phyllanthus Niruri L Extract As Substitute Alternative Flumequin Antibiotic To E. Coli On Broiler
  10. The Effects Of Propolis On Histopatological Liver In Male Mice (mus Musculus)
  11. Antibacterial Potential Of Euphorbia Hirta L. Extracts Toward Staphylococcus Aureus Growth Through In Vitro Method
  12. Rosella (hibiscus Sabdariffa Linn) Extract As Hepatoprotector On Lead Poisoning

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