UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 50 / No. 2 / Published : 2014-04

Order : 2, and page :67 - 72

Related with : Scholar   Yahoo!   Bing

Original Article :

Correlation between plasma levels of interferon and viral load in patients with hiv stage 1

Author :

  1. Hermi Indita Malewa*1
  2. Endang Retnowati*2
  3. Erwin Astha Triyono*3
  1. Resident at the Department of Clinical Pathology Faculty of Medicine, Airlangga University, Dr Soetomo Hospital, Surabaya
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

The incidence of HIV in Indonesia is on the increase and in Asia, Indonesia is considered as the most rapid. One of the diagnostictools for diagnosing HIV is viral load. Lymphocyte T-CD8 + secreted IFN- will inhibit replication of HIV virus through induction ofantiviral protein and host immune response which kills infected cells. Examination of IFN- plasma and viral load will be moreconfincing for the treatment and/or to knowing the progressiveness of HIV & AIDS. The aim of the study is to know the correlationbetween IFN- plasma and viral load in stage 1 HIV patients. Forty two samples from HIV patients were collected at theIntermediate Care and Infectious Disease Unit, Dr. Soetomo Hospital, Surabaya from April to June 2011. The concentration of IFN- plasma was measured by ELISA (eBioscence) method and amount of viral load was measured using PCR Cobas Amplicor (RocheDiagnostics). The level of IFN- plasma was 11.4 pg/ml to 576 pg/ml and the level of viral load was 589 copies/ml to 510,000copies/ml. The statistical analysis showed no significant correlation (p>0.05) between IFN- plasma level and viral load in stage 1HIV patients. No correlation was found between IFN- plasma and viral load in stage 1HIV patients. (FMI 2014;50:67-72)

Keyword :

IFN-, viral load, stage 1 HIV,


References :

Gab JK, Hak SL, Kee-Jong H, Sung SK,(2010) Dynamic correlation between CTL response and viral load in primary human immunodeficiency virus-1 infected Koreans - : Virol

Handojo I,(2003) Pengantar Imunoasai Dasar Surabaya : Airlangga University Press





Archive Article

Cover Media Content

Volume : 50 / No. : 2 / Pub. : 2014-04
  1. The Effect Of 3000 Mg Intravenous Vitamin C On Serum Nitric Oxide Level Of Severe Burnt Injury Patients
  2. Correlation Between Plasma Levels Of Interferon And Viral Load In Patients With Hiv Stage 1
  3. Correlation Between Serum Level Of Heart Type Fatty Acid Binding Protein (h-fabp) And N-terminal Pro-brain Natriuretic Peptide (nt-probnp) On Acute Coronary Syndrome Patient
  4. Profile Of Gyra And Gyrb Gene Mutation In Clinical Isolate Of Ciprofloxacin Resistant Pseudomonas Aeruginosa
  5. Effect Of Cardiac Rehabilitation Programs On Functional Capacity Of Post Coronary Revascularization Patient Using Six Minute Walk-test
  6. Correlation Between Tgf-1 Plasma Level And Cd4+ T Lymphocyte Count In Stage I Hiv-infected Patients
  7. The Effect Of 3000 Mg Vitamin C Infusion On Histamine Level Of Severely Burnt Patients
  8. Comparison Of Fugl-meyer Score Between Patients With Acute Thrombotic Infarc Stroke Treated With Standard Medication And Fluoxetine
  9. Antibiotics Quantity-based Escherichia Coli Resistance Pattern In Patients At Surgical And Psychiatric Wards, Dr Soetomo Hospital, Surabaya
  10. Age And Resting Heart Rate Are Discriminators To Predict Endurance Without Physical Test
  11. Case Report: Trunk And Reticular Varicose On A 9-year-old Child
  12. Comparison Of The Apgar Score Of Spontaneous Vaginal Birth And Assisted Birth In Dr. Soetomo Hospital Surabaya
  13. Five Years Retrospective Study Of Burns In Dr Soetomo General Hospital Surabaya

Information FMI