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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 47 / No. 1 / Published : 2011-01

TOC : 7, and page :30 - 35

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Original Article :

Correlation of histopathological skin biopsies with clinical diagnosis in leprosy

Author :

  1. Fauziah Nuraini Kurdi*1
  2. R Pamudji*2
  3. Heni Maulani*3
  4. Heni Sulastri*4
  1. Physical and Health Study Program, Teacher Training and Education Faculty and Rehabilititative Medicine, Medical Faculty, Sriwijaya University, Palembang
  2. Department of Dermatology and Venereology, Dr A Rivai Leprosy Hospital in Sei Kundur, Mariana, Palembang
  3. Department of Anatomic Pathology, Medical Faculty, Sriwijaya University, Palembang
  4. Department of Anatomic Pathology, Medical Faculty, Sriwijaya University, Palembang

Abstract :

This study was carried out to compare between diagnosis of leprosy for research clinically using Ridley Jopling criteria with laboratory examination. Eighty five patients who visits outpatient clinic in Dr.A.Rivai Leprosy Hospital in Sei Kundur Mariana Palembang diagnosed clinically using Ridley Jopling criteria and histopathologically from their skin biopsies based on the illustrated manual "Leprosy in the light skin" by D.L. Leiker and E. Nunzi, published by AIFO (Italy). Correlation between diagnosis based on skin biopsies and clinical diagnosis using Ridley Jopling classification was studied. There was agreement in 50 % of cases. The correlation was highest in IL (100% ) followed by BL (77.7%), BT (62.5 %), TT (58 of .3.6%), LL (53.8%), and BB (7.69 %). The other interesting observation was that only 2 of BB cases diagnosed clinically but histopathologically found 13 cases. That mean the ability or precesision of clinical diagnosis to identify of early leprosy is 15.4 % only.

Keyword :

leprosy, Ridley-Jopling classification, histopathology,


References :

  1. Harboe M. , (1994). Overview of host-parasite relations. In: Hastings RC, Opromolla DVA. Eds. Leprosy, 2nd edition. New York : Churchill Livingstone
  2. Jerath VP, Desai SR. , (1982). Diversities in clinical and histopathological classification of leprosy. : Lepr India
  3. Jopling WH, McDougall AC, (1996). Handbook of leprosy, 5th edition. Delhi : CBS Publishers and Distributors


   


Archive Article

Cover Media Content

Volume : 47 / No. : 1 / Pub. : 2011-01
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  2. Sex determinant of human hair with dna analysis method using polymerase chain reaction (pcr)
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  5. Decrease of cross shift and cross week blood cholinesterase activity in pesticide sprayer of onion farmers
  6. Identification of mycobacterium tuberculosis adhesion protein in sputum of tuberculous patients
  7. Correlation of histopathological skin biopsies with clinical diagnosis in leprosy
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