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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 46 / No. 4 / Published : 2010-10

TOC : 3, and page :247 - 252

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Original Article :

Description of blood viscosity from diabetes mellitus outpatients in endocrine clinic, aw sjahranie hospital, 2009

Author :

  1. Caropeboka LC*1
  2. Kalalo LP*2
  1. OPD, Endocrine Division, Departement of Internal Medicine
  2. Departement Clinical of Pathology Faculty of Medicine, Mulawarman University AW Sjahranie Hospital, Samarinda

Abstract :

In Diabetes Mellitus (DM), the presence of chronic uncontrollable hyperglycemia, fat and protein metabolic disorder and damaged blood components generate blood haemoconcentration and hyperviscosity. Blood hyperviscosity in DM patients may influence blood stream, so that it will generate and enhance the plague formation at venous wall and facilitate the thrombus formation. This, in turn, may lead to serious complications for example stroke, myocard infarction, vascular damages, kidney failure, retinopathy and the peripheral artery disease (PAD) occurance. This study objective was to find the description of blood viscosity in patients with DM. This was a descriptive observational study by taking samples that meet the sample criteria, involving 105 patients DM outpatients at Endocrine Clinic, Internal Medicine Departement, AW Sjahranie Hospital, Samarinda, from September1st to October 1st 2009. Data were obtained from the blood viscosity tests and the patients' medical record. In 105 DM patients the blood viscosity values were between 1.8-7.3 CP with average blood viscosity of 3.9 CP (SD 0.87). Blood viscosity frequency increased (>5.1 CP) in 10 patients (9.5%), blood viscosity was normal (3.5-5.1 CP) in 59 patients (56.2%), and decreased (<3.5 CP) in 36 patients (34.3%). Blood viscosity frequency increased in patients with acquired pure DM 3 people (2.9%) and DM with hypertension was found in 7 patients (6.7%). In conclusion, factors affecting blood viscosity are hematocrit, protein plasma, temperature, blood flow, blood vessel size, blood pressure, erythrocyte, and blood components. Viscosity disorder may lead to the several vital organs damage, such as kidney, heart, brain and retina.

Keyword :

diabetes mellitus, blood viscosity,


References :

  1. Benyamin, Andi F, Gustaviani R, (2006). Gangguan hemostasis pada diabetes melitus. In: Setiyohadi B, Alwi I, Sudoyo AW (eds). Buku Ajar Ilmu Penyakit Dalam. 4th ed.. Jakarta : Pusat Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia
  2. Ercan, et al., (2002). The Effects of cholesterol levels on hemorheological parameters in diabetic patients. - : Clinical Hemorheology and Microcirculation
  3. Guyton AC and Hall JE, (1997). Metabolisme lemak. In: Setiawan I (ed). Buku Ajar Fisiologi Kedokteran, 9th ed. . Jakarta : EGC


   


Archive Article

Cover Media Content

Volume : 46 / No. : 4 / Pub. : 2010-10
  1. Contribution of lifestyle and obesity to the incidence of pre-diabetes
  2. The importance of parenting on growth and development in toddlers
  3. Combination of metformin and hyperbaric oxygen therapy increased enos concentration
  4. Description of blood viscosity from diabetes mellitus outpatients in endocrine clinic, aw sjahranie hospital, 2009
  5. 2-methoxyethanol exposure affects protein profile of testicular sperm membrane in mice (mus musculus)
  6. Extract of psidium guajava leaves reduces malondialdehyde in soleus muscle of wistar rats directly after acute physical activity
  7. Occupational health and safety behavior analysis and nosocomial infection risk in cleaning service workers at dr. seotomo hospital surabaya
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  13. Non-specific pattern of ultrasonogram (usg) in lymphoma of the breast
  14. Hormonal status (estrogen receptors - progesterone) and her-2 neu in various cyclin d1 expressions in breast cancer