UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 42 / No. 1 / Published : 2006-01

Order : 2, and page :6 - 14

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Original Article :

Effect of laser at pishu point on amount and function of pancreatic β cells (rattus norvegicus) injected by streptozotocin

Author :

  1. Abdurachman*1
  1. Department of Anatomy and Histology Airlangga University School of Medicine Surabaya

Abstract :

This study has an objective to obtain experimental laboratory proof on the effect of laser at pishu point (BL-20) in order to increase the number of ß pancreatic cells, enlarge the width of Langerhans’ islets and improve the function of ß cells. The increase of ß cell number and functions was examined using immunohistochemical method to insulin inside the cells. Normal insulin function in the cells was observed from fasting blood glucose. This was a laboratory experimental study using randomized the posttest-only control group design. This study was carried out in Experimental Animal Unit, Department of iochemistry, Airlangga University School of Medicine. A number of 22 rats were divided into two groups. Control group comprised DM rats due to STZ induction, and treatment group comprised STZ-induced DM rats receiving laser at pishu point. Statistical analyses were independent t-test and Spearman's correlation test. It was found that the percentage of pancreatic ß cells and the width of Langerhans’ islets were significantly higher in treatment group (p < 0.05), while fasting blood glucose level was significantly lower in experimental group (p < 0.05). Furthermore, a strong correlation (p < 0.5) was found between the increase of ß cells count, the increased width of Langerhans’ islets and the reduction of fasting blood glucose level. It indicated that the effect of laser at pishu point in STZ-induced DM rats increase the number as well as the function of ß cells.

Keyword :

Laser, DM, STZ, ß cells,


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Archive Article

Cover Media Content

Volume : 42 / No. : 1 / Pub. : 2006-01
  1. Toxoplasma gondii infection elicits the increase of fas expression on the trophoblast associated with the increase of trophoblast apoptosis
  2. Effect of laser at pishu point on amount and function of pancreatic β cells (rattus norvegicus) injected by streptozotocin
  3. The effects of unilateral urethral obstruction on tubular cells apoptosis:an experimental study in rabbits
  4. Antimicrobial activities of andrographolide and propolis against intracellular mycobacterium tuberculosis phagocytosed by monocytes derived macrophages
  5. The 2-methoxyethanol toxicity towards the structures of plasma membrane and mitochondria of the rat’s spermatozoa
  6. Genotyping of extended spectrum Β-lactamase escherichia coli strains from clinical specimens
  7. Multiresistance pattern of extended spectrum β-lactamase (esbl) – escherichia coli and klebsiella pnemoniae strains
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  9. Trachoma in pondok pesantren salafiyah syafiiyah, sukorejo, situbondo, east java. a case study
  10. Review article : depression in post-myocardial infarction patients
  11. Review article and clinical experience: the mets: one of the major threat to human health