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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 39 / No. 4 / Published : 2003-10

TOC : 3, and page :214 - 215

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Original Article :

Expression of bcl-2 and p53 in uterine cervical cancer

Author :

  1. Endang Yoewarini*1
  1. Department of Pathology Airlangga University School of Medicine Dr Soetomo Teaching Hospital, Surabaya

Abstract :

The uterine cervix is potentially serious upper genital tract infection and a target for viral and other carcinogen, which may lead to invasive carcinoma. Squamous cell carcinoma of the uterine cervix may occur at any age from the second decade of live to senility. The author studied 20 cases of cervical carcinoma (Squamous cell carcinoma type), fixed in formalin embedded in paraffin. Immunohistochemistry was carried out using the avidin-biotin immunoperoxidase technique for p53 and bcl-2. Positive of p53 expression was detected all of the cases and bcl-2 expression was detected in 12 of 20 cases squamous cell carcinoma of the cervical cancer.

Keyword :

p53, bcl-2, uterine cervical cancer, squamous cell carcinoma,


References :

  1. Benjamin I, (1996). Expresion and mutational analysis of p53 in cervical cancer . - : Am J Obstet and Gynecol
  2. Iggo R, Gatter K, Bartek J, Harris AL, (1990). Increased expression of mutant forms of p53 oncogene in primary lung cancer. - : Lancet


   


Archive Article

Cover Media Content

Volume : 39 / No. : 4 / Pub. : 2003-10
  1. Editorial vol 39 no 4 2003
  2. Opinion: medical molecular surgery
  3. Expression of bcl-2 and p53 in uterine cervical cancer
  4. The pattern of immunopathobiological response in oral mucosa to disclose the immunopathobiogenesis of candida albicans infection in patients with diabetes mellitus
  5. Efficacy of low dose sublingual immunotherapy in childhood asthma
  6. Stature and weight of indonesian children compared to nchs-reference
  7. Review article and clinical experience: the roles of micronutrients in the treatment of diabetes mellitus (focus on chromium and specific nutrients)
  8. The latest clinical epidemiological data of ischemic and hemorrhagic stroke patients in surabaya and the surroundings a hospital-based study
  9. Postnatal depression in three hospitals in surabaya
  10. The attitude improvement among community health center staff in managing the risk and resolving malnutrition in underfives by using estimation score
  11. The difference between adolescents with and without conduct disorder in assessing their family function
  12. Subtotal pancreatectomy for persistent hyperinsulinemia hypoglycemia in neonate (a case report)