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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 49 / No. 4 / Published : 2013-10

TOC : 11, and page :263 - 267

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Original Article :

Hearing disorder in multidrug-resistant tuberculosispatients atthe outpatients unit, pulmonary department, dr. soetomo hospital surabaya

Author :

  1. Elida Mustikaningtyas*1
  2. Nyilo Purnami*2
  1. Dosen Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran

Abstract :

Until now, examination of hearing loss degree in patients with MDRTB who received TB treatment has not been done. It is importantto prevent the effects of TB drugs against hearing loss or deafness. The results of the study on center TB hospitals at Beatrixoord inJanuary 1995 through July 2000 showed the prevalence of hearing loss due to ototoxic was quite large, 41%. This study is aretrospective descriptive study to obtain the incidence of hearing loss in MDRTB patients were performed at pulmonary division Dr.Soetomo Hospital Surabaya. The data was taken from patients visited from 1 January2009 through 31 December 2011. In general,there were 41 MDRTB patients with age range 22-60 years old. Mainly, patients were in the age group 31-40 years old(36.6%).Mostly they were treatment failure patients, 18 people(44%), relapsed patients as many as 13 people(31.6%), and inattentive 10people24.4%). From the anamnesis, hearing complaints obtained at 19 people(46.3%), and 22 people(53.7%) did not feel anycomplaints. Using audiometric examination, found mild hearing loss in 39 ears (48%), moderate 20 ears (24%), moderate severe 3ears(4%), severe 1 ear(1%), very severe 12 ears(15%), and normal only 7 ears(8%). While the examination obtained by using OAE,there were 23 ears(28.04%) with normal cochlea, 45 ears(54.87%) suffered cochlea disorder, and 14 ears(17.07%) were notexamined.Kanamycin injections as TB drugs suspected to result ototoxic, resulting in hearing loss in MDRTB patients.(FMI2013;49:263-267)

Keyword :

Multidrugs-Resistant Tuberculosis, Ototoxic, Audiogram, Otoacoustic Emission,

References :

  1. Duggal P and Sarkar M, (2007). Audiologic monitoring of multi drug resistant tuberculosis patients on aminoglycoside treatment with long term follow up. - : BMC Ear Nose Throat
  2. Jager PD and Altena RV, (2002). Hearing loss and nephrotoxicity in long term aminoglycoside treatment in patients with tuberculosis. Retrospective chart study. - : Int J Tuberc Lung Dis


Archive Article

Cover Media Content

Volume : 49 / No. : 4 / Pub. : 2013-10
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  2. The effect of lime peel extract (citrus aurantifolia) to total blood cholesterol levels of mice (mus musculus) that given the high cholesterol diet
  3. Monitoring of potassium level on the heart failure patients using captopril and furosemide
  4. Effect of red yeast rice (monascus purpureus) extract to the trombopoietin level in dengue infected patients
  5. Amaranthus tricolor linn preserves the thickness of seminiferous tubules in mice (mus musculus) induced by lead acetate
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  7. Profile of chest and abdomen ultrasound on patients with dengue virus infection in dr. soetomo hospital surabaya between february-april 2012
  8. The prevalence of extended spectrum beta-lactamase (esbl) in third generation cephalosporin usage among sepsis patients in the department of internal medicine rsud dr. soetomo surabaya
  9. Case report: management of peptic ulcer infection due to helicobacter pylori infection and abscess liver bowel perforation
  10. Difference of pain intensity in tension type headache patients focusing on the personality
  11. Hearing disorder in multidrug-resistant tuberculosispatients atthe outpatients unit, pulmonary department, dr. soetomo hospital surabaya
  12. The difference of heart rate recovery among obese subjects with and without metabolic syndrome
  13. Dysfunction of cochlear and retrocochlear with tinnitus in normal hearing