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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 49 / No. 4 / Published : 2013-10

TOC : 3, and page :216 - 219

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Original Article :

Monitoring of potassium level on the heart failure patients using captopril and furosemide

Author :

  1. Titi Agni H*1
  2. Suharjono*2
  3. Mohammad Aminuddin*3
  1. Mahasiswa Fakultas Farmasi
  2. Dosen Fakultas Farmasi
  3. Dosen Fakultas Kedokteran

Abstract :

This study was conducted to monitor potassium levels in patients with heart failure NYHA type III-IV with administration ofcombination therapy of captopril and furosemide in areas of inpatient wards of dr. Soetomo General Hospital. This study is aprospective observational study. The samples were heart failure patients with NYHA type III and IV in Heart Care Unit of Dr.Soetomo General Hospital. Data collection was conducted from October 2011-January 2012. Study inclusion criteria are patientswith age more than 50 years and heart failure patients who received captopril and furosemide therapy. Exclusion criteria of thisresearch are cardiogenic shock, hypotension (SBP < 100 mm Hg), metabolic acidosis, patients with Diabetes Mellitus and renalfailure patients. The potassium levels results of the study with combination therapy of Captopril and Furosemide was found that 28%(9 patients) had hypokalemia, 3% (1 patient) had hyperkalemia and 69% (22 patients) with normal levels of potassium (potassiumlevels 3.5-5.0 mmol/L). It was concluded that potassium serum of heart failure patients with NYHA type III- IV who received thecombination therapy Captopril and Furosemide remain in normal and recommended use.(FMI 2013;49:216-219)

Keyword :

Captopril and Furosemide Combination Therapy, NYHA Patient type II-IV, Hyperkalemia, Hypokalemia,

References :

  1. Cohn JN et al, (2000). New guidelines for potassium replacement in clinical practice. - : Arch Intern Med
  2. Khanna A and White WB, (2009). The management of hyperkalemia in patients with cardiovascular disease. - : Am J Med


Archive Article

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Volume : 49 / No. : 4 / Pub. : 2013-10
  1. Relationship between n-terminal pro-brain natriuretic peptide (nt-probnp) level and protein st2 level in acute coronary syndrome patient
  2. The effect of lime peel extract (citrus aurantifolia) to total blood cholesterol levels of mice (mus musculus) that given the high cholesterol diet
  3. Monitoring of potassium level on the heart failure patients using captopril and furosemide
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