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Folia Medica Indonesiana

ISSN 0303-7932

Vol. 36 / No. 2 / Published : 2000-04

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Original Article :

Patient hospitalization as a risk factor for the dissemination of antimicrobial resistant microorganisms

Author :

      Abstract :

      The objective of this study is to explore the role of patients hospitalization as a risk factor for the dissemination of resistant micro-organism. The research was conducted by cross-sectional study in Dr. Soetomo Teaching Hospital Surabaya. On each hospitalized patient on Day-1 (Coded as D1) and on Day-7 (Coded as D7) a rectal swab to isolate Escherichia coli and a nose swab to isolate Staphylococcus epidermidis was performed. Then, antimicrobial susceptibility testing for 9 standard antimicrobials i.e. : ampicillin, tetracycline, gentamycin, ciprofloxacin, cefotiam, erythromycin, chloramphenicol, cefotaxime and co-trimoxazole, was done on all of the isolated bacteria. The increasing rate of antimicrobial resistance during hospitalization was then analyzed statistically. The result of this study showed that from isolates of Day-1 more than 50% of Staphylococcus epidermidis were resistant to ampicillin, tetracycline and cotrimoxazole and more than 50% of Escherichia coli were resistant to ampicillin, tetracycline, chloramphenicol and erythromycin. For isolates tested on Day-7 of hospitalization, a significant increase of antimicrobial resistance was noted, i.e. Staphylococcus epidermidis to chloramphenicol and Escherichia coli to chloramphenicol, ciprofloxacin and cefotaxime respectively. These more highly resistant bacteria will be carried by the patients when they are discharged from the hospital and will eventually lead toward a higher risk for the community to be infected by more resistant bacteria. It is concluded that the hospitalization serve as a risk factor for the increased appearance of antimicrobial resistant micro-organisms which then will tend to be disseminated into the surrounding community.

      Keyword :

      antimicrobial resistance, hospitalization, Escherichia coli, Staphylococcus epidermidis,

      References :


        Archive Article

        Cover Media Content

        Volume : 36 / No. : 2 / Pub. : 2000-04
        1. Application Of Pcr Methods For Epidemiological Studies On Malaria(1)
        2. Polyacrylamide Agarose Composite Gel Based System For Separation Of Short Tandem Repeat Loci
        3. Changes In Calcium Metabolism In End Stage Renal Disease Patient Under Regular Haemodialysis In Haemodialysis Unit Dr Soetomo Hospital, Surabaya
        4. The Role Of Immunoglobulin In The Management Of Head Injury(1)
        5. The Role Of Osteoprotegerin And Osteoprotegerin Ligand In Osteoporosis
        6. Patient Hospitalization As A Risk Factor For The Dissemination Of Antimicrobial Resistant Microorganisms
        7. Laryngeal Tuberculosis: The Diagnostic Approaches
        8. A Problem Of Malignant Lymphoma Management In Indonesia