UNIVERSITAS AIRLANGGA



Detail Article

Folia Medica Indonesiana

ISSN 0303-7932

Vol. 41 / No. 2 / Published : 2005-04

Order : 7, and page :108 - 117

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Original Article :

The effectiveness test of eyedrop lodoxamide tromethamine 0.1 % and sodium cromoglycate 2% in vernal keratoconjunctivity in dr. soetomo hospital, surabaya

Author :

  1. Sjamsu Budiono*1
  1. Department of Ophthalmology Airlangga University School of Medicine Dr Soetomo Teaching Hospital, Surabaya

Abstract :

A study on the effectiveness of Lodoxamide Tromethamine 0.1% and Sodium Cromoglycate 2% has been conducted to 36 patients with vernal keratoconjunctivity in Ophthalmologic Outpatient Clinic, Dr Soetomo Hospital, Surabaya, from August 1999 to February 2000. The patients were divided into 2 groups, i.e., Lodoxamide and Cromoglycate groups. Observation was carried out at the first, second, third, and fourth weeks. From sample distribution, it was found that most of the patients (16 individuals) belonged to age group of 1 - 5 years (44.44%), followed 15 patients in age group of 6 - 10 years (41.67%). Male patients were 32 individuals or 88.89% of all patients, higher than female ones. Atopic history was 22% in children and 19.5% in family history. Regarding the type of vernal keratoconjunctivity, the combined type was found to be the most frequent compared to the others (96.11%). Most of the samples (52.78%) suffered from vernal keratoconjunctivity for less than 1 year. Results of observation revealed significant difference in therapy effectiveness between eyedrops Lodoxamide Tromethamine 0.1% and Sodium Cromoglycate 2% in subjective complaints/symptoms (such as itch, secrete, epiphora) and objective complaints/sign (hyperemia and conjunctival edema, corneal lesion), which was varied from the first to the third week, while at the fourth week the difference was not significant. There was no significant difference in therapy effectiveness between both eyedrops in the objective symptoms (trantas dots and laboratory test). Comparative analysis on the objective symptoms (papillary hypertrophy) between both groups could not be conducted. However, significant difference was found in group given with Lodoxamide Tromethamine 0.1% before and fourth week after treatment. In group given with Sodium Cromoglycate 2%, significant difference was not found until the study was over. Side effects of the treatment were not apparent during the study.

Keyword :

lodoxamide tromethamine, sodium cromoglycate, vernal keratoconjunctivity,


References :

Allansmith MR,(1982) The Eye and Immunology London : The CV Mosby Company

David DD,(1968) Atlas of External Disease of the Eye St. Louis : The CV Mosby Company





Archive Article

Cover Media Content

Volume : 41 / No. : 2 / Pub. : 2005-04
  1. Editorial Vol 41 No 2 2005
  2. Opinion: Bioethics. Its Role In Research
  3. Gastroprotective Effect Of Curcumine On Ethanol-induced Gastric Mucosal Lesions In Rats
  4. Spermatozoa Motility And Morphological Recovery Process In Mice (mus Musculus) After The Induction Of 2-methoxyethanol
  5. Nutritional And Immune Effects Of Early Enteral Feeding Supplemented By Arginine, Glutamine And Omega 3 Fatty Acid In Critically Ill Patients
  6. The Comparison Of The Effectiveness Between 2.5% Povidone-iodine Eye Drop And 1% Tetracycline Eye Ointment On Bacterial Ophthalmia Neonatorum Prophylaxis
  7. The Effectiveness Test Of Eyedrop Lodoxamide Tromethamine 0.1 % And Sodium Cromoglycate 2% In Vernal Keratoconjunctivity In Dr. Soetomo Hospital, Surabaya
  8. Risk Factors Of Symptomatic And Asymptomatic Osteoarthritis Of The Knee
  9. Brain Natriuretic Peptide As An Indicator Of Left Ventricle Dysfunction And A Predictor Of Cardiovascular Events In Acute Coronary Syndromes
  10. Management Of Perioperative Pulmonary Edema In Patient With Pre-eclampsia/eclampsia Undergoing C-section
  11. Water Source As The Risk Factor Of H. Pylori Infection In Chidren Aged 0 - 5 Years In Suburban Area Of Surakarta
  12. Clinical–epidemiological Data On Hiv/aids Patients Admitted To A Top Referral Hospital During 1997-2005. A Database For Action In The Future, Referring To Another Developing Countries
  13. Review Article And Clinical Experience: New Insights Into Oral Agents In The Treatment Of T2dm (the Roles Of Fixed-dose Oral Agents Combination)
  14. Literature Review: Choosing A Prosthetic Heart Valve

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