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Detail Article

Indonesian Journal of Medical Microbiology

ISSN

Vol. 1 / No. 1 / Published : 2012-12

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Original Article :

Antimicrobial activity of hibiscus sabdariffa calyx extract against shigella dysenteriae in vitro

Author :

  1. Rengganis Prastami Mumpuni*1
  2. Eddy Bagus Wasito*2
  3. Ratna Sofaria Munir*3
  1. Faculty of Medicine, Airlangga University, Surabaya
  2. Department of Microbiology, Faculty of Medicine, Airlangga University, Surabaya
  3. Department of Pharmacology and Pharmacy, Faculty of Medicine, Airlangga University, Surabaya

Abstract :

Each year, 80 million cases of bacillary dysentery is found. It causes 700,000 deaths worldwide. Bacillary dysentery due to Shigella dysenteriae infections show the most severe clinical symptoms and become epidemic on wide areas. In Indonesia, it began to be a reemerging disease. Meanwhile, there is emerging drug resistance of Shigella dysenteriae to several drugs which are originally used to cure its infection such as co-trimoxazole. Extracts of Hibiscus sabdariffa calyx is known to have antimicrobial activity against several strains of bacteria. Therefore, the researcher conducted a study of the antimicrobial activity of Hibiscus sabdariffa calyx extract against Shigella dysenteriae. This study determines the antimicrobial potential of Hibiscus sabdariffa calyx extract against Shigella dysenteriae.Hibiscus sabdariffa  calyx were extracted with methanol and divided into 6 concentrations. Antimicrobial activity assay performed with the dilution method in Mueller Hinton broth medium.The result of this research isShigella dysenteriae did not grow in all tubes with extract concentration of 0.5 ml/ml up to 0.03 ml/ml and negative control tubes. Shigella dysenteriae grew in tubes containing the extract of Hibiscus sabdariffa with concentration of 0.015 ml/ml and positive control tubes. It can be concluded that extract of Hibiscus sabdariffa calyx extract have antimicrobial activity against bacteria Shigella dysenteriae at minimum concentration of 0.03 ml / ml.

Keyword :

antimicrobial, Hibiscus sabdariffa calyx extract, Shigella dysenteriae,


References :

  1. WHO, (2005). for the Control of Shigellosis, Including Epidemics Due toShigella dysenteriae Type 1. Geneva : WHO Press


   


Archive Article

Cover Media Content

Volume : 1 / No. : 1 / Pub. : 2012-12
  1. Antimicrobial activity of hibiscus sabdariffa calyx extract against shigella dysenteriae in vitro
  2. Bactericidal effect of cempedak (artocarpus champeden) stem extract on mycobacterium tuberculosis
  3. Antibacterial activity of papaya leaves (carica papaya,l) infusum against escherichia coli
  4. Ziehl neelsen stain sensitivity in determining the etiologic of granulomatous inflammation
  5. Comparative antibacterial activity of noni fruit versus ciprofloxacin against salmonalla typhii in vitro
  6. Susceptibility pattern of mycobacterium tuberculosis from bronchoalveolar lavage (bal) specimen