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Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 7 / No. 1 / Published : 2018-06

TOC : 9, and page :62 - 69

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Original Article :

Effectiveness of binahong leaves gel ekstrak (anredera cordifolia (tenore) steenis) to burn wound of mice (mus musculus) on inflammation observation

Author :

  1. Cyntia Dewi Retno Indriani *1
  2. Iwan Sahrial Hamid*2
  3. Sunaryo Hadi Warsito*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

Wound healing is a normal process as response to skin tissue injury. This research conducted to see the effect of binahong leaves gel extract for healing burn on mice. Divided into 4 groups, namely P0 negative control group, positive control group administered Bioplasenton P1, P2 group administered binahong leaves gel extract 10%, P3 administered binahong leaves gel extract 20%. By making a burn on the right side of the mice’s back with a wound diameter of 2 cm. Gel applied to the treatment group twice daily for 7 days. Measurements were made on days 3, 5 and 7 by using a sliding range. Data were analyzed by Kruscall-Wallis test and continued by Mann-Whitney test. The results showed that the binahong leaves gel extract was able to heal burns on the administration of Bioplasenton and 20% concentrated gel, the burn diameter decreased and inflammation process occured at day 7, then the higher concentration of extracts gave more healing effect on burns (p<0,05).

Keyword :

Binahong leaves gel extract, Burns, Inflammation, Bioplasenton, Mice,

References :

  1. Betz, C.L and Sowden, L. A, (2009). Buku Saku Keperawatan Pediatri . Edisi 5 : Jakarta : EGC
  2. Gibson, M, (2001). Pharmaceutical Preformulation and Formulation,. 546-550 : CRC Press, United States of America.
  3. Pusponegoro AD,, (2005). Luka. Dalam: Sjamsuhidajat R, De Jong W, Penyunting. Buku Ajar Ilmu Bedah.. Edisi 2 Hal. 66-88 : Jakarta: EGC


Archive Article

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Volume : 7 / No. : 1 / Pub. : 2018-06
  1. The effect of onion (allium ceppa l.) ethanol extract to blood glucose level of rats (rattus norvegicus) induced by alloxan
  2. Antifungal activity of pomegranate peel tablet on candida albicans: an in-vitro study
  3. The effects of green tea leaves extract as nephroprotector in mice (mus musculus) that induced by mercury chloride
  4. The potential of onion (allium cepa l.) ethanol extract on the numbers of endocrine cells in the islets of white rats langerhans pancreatic tissue (rattus norvegicus) induced by alloxan
  5. The effectivity test of ethanol extract of yacon leaves (smallanthus sonchifolius) on the necrotic hepatocyte of white rat induced by alloxan
  6. The effectivity of onion (allium cepa l.) ethanol extract on kidney histopathological appearence of hyperglicemic white rat (rattus novergicus)
  7. Index of erythrocytes kintamani bali dog in east java based on mcv, mch, and mchc
  8. Description of hematological value in water monitor (varanus salvator bivittatus) in east java
  9. Effectiveness of binahong leaves gel ekstrak (anredera cordifolia (tenore) steenis) to burn wound of mice (mus musculus) on inflammation observation
  10. Effect of meniran extract (phyllanthus niruri linn) on decrase total leukocyte and number of neutrophils blood of infected broiler chick by mycoplasma gallisepticum
  11. The effect of bay leaf (eugenia polyantha) extract immersion on the total bacterial count in green mussels (perna viridis)
  12. The effect of spirulina platensis on testosterone concentration of male rattus norvegicus under stress condition