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Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 4 / No. 2 / Published : 2015-12

TOC : 4, and page :100 - 105

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Original Article :

Infusum cincau green leaves as the use inflammatory gastric on white rat (rattus norvegicus ) induced use caffeine with inspection histopathology

Author :

  1. Sherly Maubella*1
  2. Intan Aprilia A. *2
  3. Wildan Ramadhan*3
  4. Romy Muhammad Dary Mufa*4
  5. Bagus Aditya K*5
  6. Hani Plumeriastuti*6
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Mahasiswa Fakultas Kedokteran Hewan
  3. Mahasiswa Fakultas Kedokteran Hewan
  4. Mahasiswa Fakultas Kedokteran Hewan
  5. Mahasiswa Fakultas Kedokteran Hewan
  6. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of this study is to determine the effect of green grass jelly leaf infusum (Cyclea barbata Miers) as anti-inflammatory stomach in rats (Rattus norvegicus) were induced by caffeine. Twenty four male rats of Wistar strain aged 8 weeks were divided into six treatment groups, each of the 4 tail. Treatment K (-) = control, K (+) = 10 days of treatment caffeine, caffeine P1=10 days of treatment, the treatment ranitidine 7 days, P2 = caffeine 10 - day treatment, treatment infusum grass jelly leaves 25% 7 days, P3 = caffeine treatment 10 days, leaves of grass jelly infusum treatment 50% 7 days, P4 = caffeine 10-day treatment, treatment of grass jelly leaf infusum 100% 7 days. After 7 days of treatment infusum administration, the mice were sacrificed and then the pH of gastric acid was measured and histopathological examination of gastric mucosa which includes ulceration, inflammatory and inflammatory cells. The results showed a highly significant difference (p<0.01) both pH and gastric mucosal histopathology. The best results infusum at a concentration of 50%.  

Keyword :

Infusum leaf grass jelly, caffeine, gastric, histopathology,


References :

  1. Maramis K, Rialita, , (2013). Analisis Kafein dalam Kopi Bubuk di Kota Manado Menggunakan Spektro-fotometri UV-VIS.. 1-6 : Jurnal Ilmiah Farmasi UNSRAT. Manado
  2. Djam’an, Qathrunnada. , (2008). Pengaruh Air Perasan Daun Cyclea barbata Miers (Cincau Hijau) Terhadap Konsentrasi HCL Lambung dan Gambaran Histopatologik Lam¬bung Tikus Galur Wistar yang Diinduksi Acetylsalicylic acid. . 2-8 : Uni¬ver¬sitas Diponegoro. Semarang.


   


Archive Article

Cover Media Content

Volume : 4 / No. : 2 / Pub. : 2015-12
  1. The effect of giving vitamin c on endosulfan induced in histopathologic liver of mice (mus musculus)
  2. Influence of hibiscus sabdariffa l. calyx on alveolar histopathological feature of cigarette smoke exposed mice
  3. The effect of l-arginine orally on the the histologycal of seminiferous tubules of rabbit (oryctolagus cuniculus) testicular
  4. Infusum cincau green leaves as the use inflammatory gastric on white rat (rattus norvegicus ) induced use caffeine with inspection histopathology
  5. The influence of sambiloto leaf (andrographis paniculata) extract as an imunostimulator against the proliferation of lymphocyte
  6. Effects of plant wood yellow leaf extract (arcangelisia flava merr) as to prevent hepatic dysfunction examination levels of bilirubin, sgot sgpt and serum blood on white rat (rattus norvegicus)
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  9. Antibacterial activity of phyllanthus niruri l extract as substitute alternative flumequin antibiotic to e. coli on broiler
  10. The effects of propolis on histopatological liver in male mice (mus musculus)
  11. Antibacterial potential of euphorbia hirta l. extracts toward staphylococcus aureus growth through in vitro method
  12. Rosella (hibiscus sabdariffa linn) extract as hepatoprotector on lead poisoning