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Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 3 / No. 1 / Published : 2014-06

TOC : 2, and page :8 - 13

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Original Article :

The effect of infusion of tekelan (chromolaena odorata l.) leaf to wound healing incision on mice (mus musculus) were infected by staphylococcus aureus

Author :

  1. Tarman*1
  2. Iwan Syahrial Hamid*2
  3. Nanik Sianita Widjaja*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

This research was conducted to investigate the ability of infusion of tekelan (Chromolaena odorata L.) leaf, as a medicinal plant for wound healing incision on mice were infected by Staphylococcus aureus. Twenty five of two months old male mice BALB/c strain with 25-30 gram average body weight was divided into five group P0; P1; P2; P3; and P4. P0 was negative control was not given treatment, P1 was positive control was given Povidone Iodine 10%, and P2, P3, P4 was given concentration 5%, 10%, 20% of tekelan leaf infuse. Each treatment was consisted of 5 mice. Observation of wound healing was characterized by wound closure of epithelial tissues. The experimental design used in this study was using completely randomized design (CRD). The data were analyzed by Kruskal-Wallis Statistic Method and then was followed by Mann Whitney test with a significance of 5%. The result showed the infusion of tekelan leaf increased wound healing incision on mice were infected by Staphylococcus aureus. The best results were shown by the treatment test of tekelan leaf infusion with concentration of 20%.     

Keyword :

Tekelan, infusion, wound healing, infection,


References :

  1. Depkes RI. , (1995). Farmakope Indonesia Ed. IV.. Jakarta : : Depkes RI
  2. Plata K, Rosato A.E, Wegrzyn G. . , (2009). Staphylococcus aureus as an infectious agent: overview of biochemistry and molecular gene¬ tics of its pathogenicity... Polonica : Acta Biochimica Polonica 56(4) : 597–612
  3. Saroja, M., Santhi, R., Annapoorani, S. . , (2012). Wound Healing Activity of Flavonoid Fraction of Cynodon Dactylon in Swiss Albino Mice. . Swiss : Int Res J Pharm 3(2): 230-231.


   


Archive Article

Cover Media Content

Volume : 3 / No. : 1 / Pub. : 2014-06
  1. Detection of avian influenza antibody h5 subtype on bearded pig (sus barbatus) in central kalimantan
  2. The effect of infusion of tekelan (chromolaena odorata l.) leaf to wound healing incision on mice (mus musculus) were infected by staphylococcus aureus
  3. Activity test of krisan flower (chrysanthemum morifolium ramat) exstract on stable fly (stomoxys calcitrans geof.) mortality by in vitro
  4. Epidemiology of avian influenza virus (h5) from duck outbreak in the 2012-2013 in east java
  5. Identification and isolation of influenza virus (h5) in pig in north sumatra
  6. Effect of margarine and shortening trans fatty acid on rats (rattus norvegicus) hdl cholesterol level
  7. Toxicity test of ethanol extract of red roses (rosa damascena mill) by brine shrimp lethality test (bslt) method
  8. Effect of phyllanthus niruri linn extracts on blood glucose levels in diabetic rats (rattus norvegicus) induced by alloxan
  9. The effect of meniran extract (phyllanthus niruri linn.) against sgot and sgpt level of white rats (rattus norvegicus) induced by alcohol
  10. The effect of borax to duodenal histopathological changes in rats (rattus norvegicus)