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Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 4 / No. 2 / Published : 2015-12

TOC : 3, and page :94 - 99

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Original Article :

The effect of l-arginine orally on the the histologycal of seminiferous tubules of rabbit (oryctolagus cuniculus) testicular

Author :

  1. Fachruddin Aziz*1
  2. Indah Norma Triana*2
  3. Nove Hidajati*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

L-Arginine is the precursor of  nitric oxide (NO).  Nitric oxide (NO) is one of reactive oxygen species (ROS) that influencing many physiological cell signalling mechanisms in many tissues. The aim of this research was to know the effect of  l-arginine on  the seminiferous tubules diameter  as well as the epithelium thickness of seimineferous tubules of rabbit  (Oryctolagus cuniculus) . This researh used sixteen  rabbits ( 6 months old and  ± 3 kg of  body weight ) were devided into two groups, P0 and P1. P0 is a control group and P1 was given l-arginine 6g/300ml/day for 30 consecutive days. After the 30 days treatment, their testicles were harvested and processed for histological examination. The data were analyzed by Independent-Samples T Test (T test). The result  from statistical analysis showed that treatment with l-arginine has increased the diameter as well as the thickness of epithelium of seminiferous tubules of rabbit testicular significantly  (p<0.05).    

Keyword :

Seminiferous tubules, diameter and thick, l-arginine, nitric oxide,

References :

  1. Murad, F, (1994). The nitric oxide-cyclic GMP signal transduction system for intracellular and intercellular com¬munication. . 49:239-248 : Rec Progr Horm Res .
  2. Appleton, J., (2002). Arginine: Clinical potential of a semi-essential amino. .. 7(6):512–522 : Altern Med Rev2002,
  3. Clermont, Y and Perey., (2008). Quantitive Study of the Cell Population of the Seminiferus Tubules in Immature Rats. . 100 (2) : 353. : The American Journal of Anatomy


Archive Article

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Volume : 4 / No. : 2 / Pub. : 2015-12
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  2. Influence of hibiscus sabdariffa l. calyx on alveolar histopathological feature of cigarette smoke exposed mice
  3. The effect of l-arginine orally on the the histologycal of seminiferous tubules of rabbit (oryctolagus cuniculus) testicular
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