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Journal of Basic Medical Veterinary

ISSN 2302-6820

Vol. 2 / No. 2 / Published : 2013-12

TOC : 5, and page :70 - 76

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Original Article :

The effect of meniran (phyllanthus niruri linn) infusion on kidney histopathological overview of white rats (rattus norvegicus) exposed by alkohol

Author :

  1. Rista Dewiyanti Puspitaningrum*1
  2. Arimbi*2
  3. Rahaju Ernawati*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The aim of this research was to determine the effect of meniran (Phyllanthus niruri Linn)  infusion on kidney histopathological overview of white rats (Rattus norvegicus) exposed  by alcohol. The treatment divided  into 5 groups with K(+) ( 1 ml of 25 % alcohol and 1,08 mg of vitamin C) , K(-) (1ml of 25 % alcohol and 1 ml of aquadest) , P1 ( 1 ml of 25 % alcohol and 1ml of infusion meniran 10 % ), P2 ( 1 ml of 25 % alcohol and 1 ml of 20 % infusion meniran) and P3 ( Iml of 25 % alcohol and 1 ml of infusion meniran 40 % ).This study used five rat per groups on 2-3 months of age and weight between 150-200 grams.Treatment had been held for 21 days. The results showed that 40% of meniran infusion dose treatment had the smallest damage score of histopathogical overview of kidney. The conclusion of this research showed that meniran infusion can reduce and prevent the cell damage of kidney exposed by alkohol.

Keyword :

Phyllanthus niruri Linn, Infusion, Alcohol, Kidney,


References :

  1. Kardinan, A. , (2004). Meniran Menambah Daya Tahan Tubuh Alami. . . Jakar¬ta. : Agromedia Pustaka
  2. Pramavita Nur Junieva. . , (2006). Pengaruh Pemberian Ekstrak Meniran (Phy¬ l¬lanthus sp.) Terhadap Gambar¬ an Mikroskopik Paru Tikus Wistar Yang Diinduksi Karbon Tetra-klorida. . Semarang : UNDIP
  3. Rachmawati P. , (2010). . Efek Perlindungan Ekstrak Meniran Phyllantus niruri Linn.) Terhadap Kerusakan His¬to¬logis Lambung Mencit (Mus musculus) Yang Diinduksi As-pirin... Surakarta : Universitas Sebelas Maret.


   


Archive Article

Cover Media Content

Volume : 2 / No. : 2 / Pub. : 2013-12
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  2. The effect of cosmos caudatus leaf ethanol extract in liver on paracetamol induced elevation sgot and sgpt in balb/c mice
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  4. Time patern of curcuma zedoaria etract against amount of mice pulmonary nodules indusced by benzo(α)pyrene
  5. The effect of meniran (phyllanthus niruri linn) infusion on kidney histopathological overview of white rats (rattus norvegicus) exposed by alkohol
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