UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Farmasi dan Ilmu Kefarmasian

ISSN

Vol. 2 / No. 1 / Published : 2015-10

Order : 4, and page :16 - 18

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Original Article :

Isolasi senyawa terpenoid dari fraksi n-heksana daun marsilea crenata presl. pada hasil kcv fraksi no.2

Author :

  1. Yuli Puspitasari*1
  2. Suciati*2
  3. Mangestuti Agil*3
  1. Fakultas Farmasi Universitas Airlangga Surabaya
  2. Dosen Fakultas Farmasi
  3. Dosen Fakultas Farmasi

Abstract :

This research focus on isolation and identification of terpenoid fron n-hexane fraction of M. crenata Presl. leaves. M. crenata Presl. leaves was collected from Desa Kendung, Kecamatan Benowo Surabaya. The dried leaves was extracted with ethanol 96%. From this extract, a terpenoid compound was isolated. Structure identification of the isolated compound was performed by IR and 1H-NMR spectroscopy. The IR data showed that isolated compound has hydroxy, alkene and methyl group. The 1H-NMR spectrum exhibited signals at δH 4.70 and 4.65 ppm corresponding to a terminal alkene. There were signal at δH 3.63 ppm and 3.27 ppm corresponding to a hydroxy methylene and a hydroxy methyne, respectively. There are geminal dimethyl groups observed at δH 1.02 and 1.00 ppm, while a cyclopropane suggested from signals at δH 0.54 and 0.32 ppm. 1H-NMR data comparison of the isolated compound to literature data showed that the structure of the isolated compound was similar to 24-methylenecycloartanol with a hydroxy methylene group

Keyword :

isolation, Marsilea crenata Presl., terpenoid,


References :

Kolak U, Topҫu G, Birteksӧz S, Ӧtuk G, Ulubelen A,(2005) Terpenoids and steroids from the roots os Salvia blepharochlaena Vol. 29, p.177-186 : Turk Jounal Chemistry

Mollik AH, Hossan S, Paul AK., Taufiq-Ur-Rahman, M, Jahan R, and Rahmatullah M,(2010) A comparative analysis of medicinal plants used by folk medicinal healers in three districts of bangladesh and inquiry as to mode of selection of medicinal plants Vol. 8, p. 195-218 : Ethnobotany Research & Applications

Putra HL,(2011) Green clover potentiates delaying the increment of imbalance bone remodelling process in postmenopausal women Vol. 47 No. 2, p.112-117 : Folia Medica Indonesiana





Archive Article

Cover Media Content

Volume : 2 / No. : 1 / Pub. : 2015-06
  1. Formulasi Losio Antinyamuk Dengan Zat Aktif Minyak Atsiri Lantana Camara Linn
  2. Development Potentiometric Sensor-coated Wire Cyanide Ion Selective Electrode Based Aliquat336 Membranes For Determination Cyanide In Gadung (dioscorea Hispida Dennus)
  3. Studi In Silico Gendarusin A, B, C, D Dan E Untuk Prediksi Aktivitas Terhadap Enzim Cyp17a1 Sebagai Afrodisiaka
  4. Isolasi Senyawa Terpenoid Dari Fraksi N-heksana Daun Marsilea Crenata Presl. Pada Hasil Kcv Fraksi No.2
  5. Pengaruh Pasta Tomat (solanum Lycopersicum L.). Pada Pertumbuhan Dan Daya Hambat Lactobacillus Acidophilus Fncc-0051 Dan Lactobacillus Plantarum Fncc-0027 Terhadap Candida Albicans
  6. Aktivitas Antibakteri Susu Probiotik Lactobacilli Terhadap Bakteri Penyebab Diare (escherichia Coli, Salmonella Typhimurium, Vibrio Cholerae)
  7. Aktivitas Penghambat Asetilkolinesterase Ekstrak Etanol 96 Persen Daun Syzygium Cumini, Syzygium Aromaticum, Syzygium Polyanthum Dan Syzygium Aquaeum