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VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 6 / No. 1 / Published : 2017-08

TOC : 9, and page :40 - 44

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Original Article :

Effectiveness of binahong leaves gel extract (anredera cordifolia (ten.) steenis) to reduce the number of pmn cells in incision wound healing processes of male mice (mus musculus)

Author :

  1. Merynda Mega Kusuma*1
  2. Iwan Sahrial Hamid*2
  3. Djoko Legowo*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of this study was to learn about the effectivenesss of binahong leaves gel extract to reduce the number of PMN cells in incision wound healing process of male mice (Mus musculus). Twenty male mice (Mus musculus) were divided into four groups i.e P0 (HPMC 3%), P1 (Povidone iodine), P2 (binahong leaves gel extract with 10% concentration) and P3 (binahong leaves gel extract with 20% concentration). All of treatment was done for three days (72 hours). Histopathological examination was done and data analysis used ANOVA followed with Duncan test. The analysis showed there was significant difference between P0 with P1, P2 and P3 (p<0.05), that P0 has mean and standard deviation 357.8 ± 75.98, P1 128.6 ± 11.3, P2 112.4 ± 11.63 and P3 70.6 ± 7.23. The results showed that P0 has significant difference with P1, P2 and P3, P1 insignificance different with P2 but significant difference with P3, and P2 insignificance different with P3. The conclusion of this study was binahong leaves gel extract can reduce the number of PMN cells in incision wound healing of male mice (Mus musculus), the best result in this study to reduce the number of PMN cells was binahong leaves gel extract with 20% concentration.

Keyword :

mus musculus, binahong leaves gel extract, PMN, wound healing incision,


References :

  1. Ariani, S., Loho, L., dan Durry, M.F., (2013). Khasiat Daun Binahong (Anredera cordifolia (Ten.) Steenis) terhadap Pembentukan Jaringan Granulasi dan Reepitelisasi Penyembuhan Luka Terbuka Kulit Kelinci.. 1(2), 914-919. : Jurnal e-Biomedik
  2. Astuti, S.M., (2011). Determination of saponin compound from Anredera cordifolia (Ten.) Steenis plant (Binahong) to potential treatment for several disease. . Vol. 3(4): 224-232. : Journal of Agricultural Science.
  3. Ekavianti TA, Fachriyah E. dan Kusrini D. , (2013). Identifikasi asam fenolat dari ekstrak etanol daun binahong (Anredera cordifolia (Ten.) Steenis) dan uji antioksidan. . Vol. 1(1): 283-293. : Chemical Information:
  4. Wilgus, T.A., Vodovotz, Y., Vittadini, E., Clubbs, E.A., dan Oberyszyn, T.M., (2003). Reduction of Scar Formation in Full-thickness Wounds with Topical Celecoxib Treatment. . 11, 25-34. : Wound Repair Regeneration


   


Archive Article

Cover Media Content

Volume : 6 / No. : 1 / Pub. : 2017-07
  1. The case of digestive disorders in older cat (felis catus) based on medical history records at veterinary teaching hospital faculty of veterinary medicine universitas airlangga surabaya period 2014 -2016
  2. The potential for environmental pollution from the feces of worm infected dogs in surabaya
  3. The effectivity of gel extract binahong leaf (anredera cordifolia (ten.) steenis) on the incision wound in mice (mus musculus) by observation of wound area leangth and wound healing
  4. The effect of laserpuncture on heart rate, respiratory rate, body temperature and energy cost of locomotion of indonesian thoroughbred horse
  5. Comparison of hematologic value between kintamani dogs (canis lupus familiaris) and local dogs (canis familiaris)
  6. The effect of kikolod (isotoma longiflora (l) presl.) leave's extractto histopatology of incision wound healing in mice (mus musculus)
  7. The effect of okra (abelmoschus esculentus) extract ointment on topically on the rate wound healing process of skin burn on rat (rattus norvegicus) as model animals
  8. The influence of gel extract binahong leaf (anredera cordifolia (ten.) steenis) to observe macrophague cells and burn wound diameter degree ii in mice (mus musculus)
  9. Effectiveness of binahong leaves gel extract (anredera cordifolia (ten.) steenis) to reduce the number of pmn cells in incision wound healing processes of male mice (mus musculus)