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VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 1 / No. 1 / Published : 2012-07

TOC : 2, and page :5 - 8

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Original Article :

Histopathology of renal male rats of femoral fracture with cissus quadrangularis plant extract and calcium carbonate therapy

Author :

  1. Julien Supraptini*1
  2. Safda Farizy Ridho*2
  3. Koesnoto SP*3
  1. Departemen Klinik Veteriner Fakultas Kedokteran Hewan
  2. Mahasiswa PPDH Fakultas Kedokteran Hewan
  3. Departemen Parasitologi Fakultas Kedokteran Hewan

Abstract :

Cissus quadrangularis is a plant used often to treat fracture and very good for bone healing process. The aim of this study was conducted renal histopathology of male rats after reposition of femoral fracture with therapy Cissus quadrangularis and calcium carbonat. This study used 18 male rats, 3 weeks of age. The rats were adaptation for a week, and than all rats were treated reposition of femoral dexter fracture with intramedullary pin fixation. The rats model were randomly divided into three groups at 2 weeks after survey. Groups I treated with normal diet, groups II with normal diet + Cissus quadrangularis 500 mg/day, and groups III with normal diet + calcium carbonate 150 mg/day. At the end of experiment all the rats were euthanized, subsequently kidney were taken out for determine the histopathological examination. The histophatological examination used Kruskall Wallis test. The results of this study indicated there was noticeable difference between Cissus quadrangularis and calcium carbonate. This study suggested the used of Cissus quadrangularis for fracture treatment was better than calcium carbonate.

Keyword :

bone fracture, Cissus quadrangularis, calcium carbonate, kidney histopathology,

References :

  1. Ira Sari Yudaniayanti, B. Sektiari, D. Galijono, (2005). Gambaran Radiografi Proses Kesembuhan Patah Tulang Femur Pada Tikus Putih Jantan Dengan Terapi Ekstrak Tikel Balung (Cissus quadrangularis). Surabaya : Laporan Penelitian
  2. Sanyal, Ahmad and Sastry, (2005). Calcite growth in Cissus quadrangularis plant extract. London : Current Science
  3. Millet, Cohen, Allen and Rushton, (1998). Bone Mineral Density Changes During Fracture Healing: A Densitometric Study in Rats. New York : Internet Journal of Orthopaedic and Related Research
  4. Legowo, DS, A Sujarwo dan LS Hamid, (1996). Dampak Penggunaan Estrogen Jangka Lama pada Gambaran Histopatologi Sel Hati dan Ginjal Serta Berat Badan Mencit Betina. Surabaya : Lembaga Penelitian Universitas Airlangga


Archive Article

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Volume : 1 / No. : 1 / Pub. : 2012-07
  1. The correlation between breed and obesity in dogs in surabaya
  2. Histopathology of renal male rats of femoral fracture with cissus quadrangularis plant extract and calcium carbonate therapy
  3. Treatment of canine demodecosis in veterinary teaching hospital faculty of veterinary medicine airlangga university
  4. Combined of ampicilline, dextran-40 and dexamethason on the prevention of intra-abdominal adhesions postoperative hysterotomy in cat (fellis catus)
  5. Packed cell volume comparison of dog blood before and after storage using citrate-phosphate-dextrose
  6. Alkaline phosphatase blood levels before and after rabbit mandibula bones reconstruction by the block of autograft decortication and non decortication technique
  7. The profil of intraocular pressure using combination ketamine-xylazine and ketamine-midazolam in rabbit (oryctolagus cuniculus)
  8. Case study : feline polycystic kidney disease