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Detail Article

VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 6 / No. 1 / Published : 2017-08

TOC : 3, and page :10 - 14

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Original Article :

The effectivity of gel extract binahong leaf (anredera cordifolia (ten.) steenis) on the incision wound in mice (mus musculus) by observation of wound area leangth and wound healing

Author :

  1. Sireen Arwa Nabeela*1
  2. Poedji Hastutik*2
  3. Iwan Sahrial Hamid*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

This research was conducted to know the effectiveness of gel extract binahong leaf on the incision wound in mice by observation of wound area length and wound healing. Mice divided into 4 treatment groups, P0 (HPMC 3%), P1 (povidone iodine), P2 (10% gel extract binahong), P3 (20% gel extract binahong). This study was observed 3 times, on day 3, day 5 and day 7 with 5 mice each observation. The data were analyzed by ANAVA followed by Duncan Test for through observation of wound area length, while Kruskal-Wallis followed by Mann Whitney Test for observation of wound healing. The result shows of wound area length on day 7, P3 very significant difference with  P0 and P1 with the mean P3 0,42, P0 0,58, and P1 0,52 but P3 significant difference with P2 0,48. The result observation of wound healing on day 3 and day 5 have a same scor 6  so there was no significant difference in all treatments (p>0,05). On day 7 shows P3 have a scor 8, the highest scor (p<0,05). Based on the analysis in the data it can be concluded that P3 the 20% concentration of gel extract binahong leaf is more effective in curing the incision because it can make wound incision become smallest and has a highest scoring of wound healing

Keyword :

binahong leaf, gel extarct, incision wound, arealength, healing,

References :

  1. Febriani, D.A., (2015). Uji aktivitas sediaan salep ekstrak etanol daun bawang putih anggur (Mansoa alliacea (Lam.) A.H.Gentry) terhadap penyembuhan luka insisi pada tikus wistar.. - : [Skripsi]. Sarjana Farmasi. Universitas Gajah Mada. Yogyakarta.
  2. Rismana, E., Rosidah, I., Prasetyawan., Bunga, O. dan Erna., (2013). Efektivitas khasiat pengobatan luka bakar sediaan gel mengandung fraksi ekstrak pegagan berdasarkan analisis hidroksipropilin dan histopatologi pada kulit kelinci. . 41(1): 45-60 : Buletin Penelitian Kesehatan.


Archive Article

Cover Media Content

Volume : 6 / No. : 1 / Pub. : 2017-07
  1. The case of digestive disorders in older cat (felis catus) based on medical history records at veterinary teaching hospital faculty of veterinary medicine universitas airlangga surabaya period 2014 -2016
  2. The potential for environmental pollution from the feces of worm infected dogs in surabaya
  3. The effectivity of gel extract binahong leaf (anredera cordifolia (ten.) steenis) on the incision wound in mice (mus musculus) by observation of wound area leangth and wound healing
  4. The effect of laserpuncture on heart rate, respiratory rate, body temperature and energy cost of locomotion of indonesian thoroughbred horse
  5. Comparison of hematologic value between kintamani dogs (canis lupus familiaris) and local dogs (canis familiaris)
  6. The effect of kikolod (isotoma longiflora (l) presl.) leave's extractto histopatology of incision wound healing in mice (mus musculus)
  7. The effect of okra (abelmoschus esculentus) extract ointment on topically on the rate wound healing process of skin burn on rat (rattus norvegicus) as model animals
  8. The influence of gel extract binahong leaf (anredera cordifolia (ten.) steenis) to observe macrophague cells and burn wound diameter degree ii in mice (mus musculus)
  9. Effectiveness of binahong leaves gel extract (anredera cordifolia (ten.) steenis) to reduce the number of pmn cells in incision wound healing processes of male mice (mus musculus)