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VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 6 / No. 1 / Published : 2017-08

TOC : 8, and page :35 - 39

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Original Article :

The influence of gel extract binahong leaf (anredera cordifolia (ten.) steenis) to observe macrophague cells and burn wound diameter degree ii in mice (mus musculus)

Author :

  1. Ikko Yunita Putri Margiyanto*1
  2. Iwan Sahrial Hamid*2
  3. Suryo Kuncorojakti*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

Binahong leaf is one of plant that has an antioxidant effect and antiinflamatory activity because it contains active compounds like Flavonoid and Saponins. The aim of this study was to examine the influence of extract gel binahong leaf toward macrophague cells and make burn wound healing process faster by observation from burn wound diameter degree II in mice. Burn wound were treatment with 10% as a (P2), 20% as a (P3) of extract gel binahong leaf compared by Bioplacenton as a (P1) and HPMC as a (P0). Everyday in 7 days treatment of burn wound diameter was recorded and then make preparation with HE staining at day 7. All the data of this study were analyzed by ANOVA and Duncan-Post Hoc Tests it showed that in day 7, P0 and P2 can’t decrease macrophague cell well with the mean in 4,15 and 3,40, it compared by P1 and P3 can decrease macrophague cell in mean 2,35 and 1,45, it also showed by percentage of diameter burn wound healing degree II in this sequence from P0, P1, P2, to P3 are 12,2%, 44,4%, 22,9%, 59,4%. The result of this study is extract gel binahong leaf with 20% concentration has had influence toward macrophague cells because it can decrease macrophague cells in proliferation phase and burn wound diameter degree II becomes smallest (p<0,05).

Keyword :

binahong leaf, gel extract, burn wound, macrofag, burn wound healing,

References :

  1. Aini, S.Q., (2014). Pengaruh Salep Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) terhadap Pembentukan Jaringan Granulasi pada Luka Bakar Tikur Sprague dawley . - : [Skripsi]. Fakultas Kedokteran dan Ilmu Kesehatan. Universitas Islam Negeri Syarif Hidayatullah
  2. Budianto, T. dan Anom P., (2014). Making Pointment of Burn Extract Etanol 96% Binahong Leaf (Anredera cordifolia (Ten.) Steenis) with Method of Maserasi.. Hal 4-5. : Jakarta.
  3. Kottaimuthu, R., Malaisamy, M., dan Ramasubbu, R., (2012). A new distribution record of Anrederacordifolia (Ten.) Steenis (Basellaceae) from High Wavy Mountains, Western Ghats.. Vol (3). Hal 142-144. : -


Archive Article

Cover Media Content

Volume : 6 / No. : 1 / Pub. : 2017-07
  1. The case of digestive disorders in older cat (felis catus) based on medical history records at veterinary teaching hospital faculty of veterinary medicine universitas airlangga surabaya period 2014 -2016
  2. The potential for environmental pollution from the feces of worm infected dogs in surabaya
  3. The effectivity of gel extract binahong leaf (anredera cordifolia (ten.) steenis) on the incision wound in mice (mus musculus) by observation of wound area leangth and wound healing
  4. The effect of laserpuncture on heart rate, respiratory rate, body temperature and energy cost of locomotion of indonesian thoroughbred horse
  5. Comparison of hematologic value between kintamani dogs (canis lupus familiaris) and local dogs (canis familiaris)
  6. The effect of kikolod (isotoma longiflora (l) presl.) leave's extractto histopatology of incision wound healing in mice (mus musculus)
  7. The effect of okra (abelmoschus esculentus) extract ointment on topically on the rate wound healing process of skin burn on rat (rattus norvegicus) as model animals
  8. The influence of gel extract binahong leaf (anredera cordifolia (ten.) steenis) to observe macrophague cells and burn wound diameter degree ii in mice (mus musculus)
  9. Effectiveness of binahong leaves gel extract (anredera cordifolia (ten.) steenis) to reduce the number of pmn cells in incision wound healing processes of male mice (mus musculus)