Catalog :




Detail Article

VetMedika Jurnal Klinik Veteriner

ISSN 2302-6499

Vol. 2 / No. 2 / Published : 2014-01

TOC : 1, and page :25 - 28

Related with : Scholar   Yahoo!   Bing

Original Article :

The root of the plant cikal tulang (cissus quadrangularis) extract in ovariectomized rats (rattus norvegicus) as an animal model of osteoporosis on levels of blood calcium

Author :

  1. Yana Pangestu*1
  2. Ratna Dhamayanti*2
  3. Ira Sari Yudaniayanti*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The aim of this study was to explore potency extract of Cikal Tulang (Cissus quadrangularis) for osteoporosis prevention in ovariectomized rat. The measured parameters were the calsium serum level. The experiment animals were twenty female rat, devided into five treatments. Five different treatment mixtures were, P0 was rat without treatment; P1 was ovariectomized rat + 0,5% CMC Na; P2 was ovariectomized rat + calcium carbonat 450 mg/kg weight + 0,5% CMC Na; P3 was ovariectomized rat + extract Cissus quadrangularis 500 mg/kg weight + 0,5% CMC Na; P4 was ovariectomized rat + extract Cissus quadrangularis 750 mg/kg weight + 0,5% CMC Na. Experimental design was used completely randomized design with five treatments and four replications. The data were analyzed using the Analysis of Variance Statistic Method and if there were differences among the treatments, The Duncan’s Multiple Range Test was used. The result indicated that there were no significant difference (p>0,05) in calcium serum levels. The conclusion showed that the effect of extract of Cikal Tulang (Cissus quadrangularis) in ovariectomized rat was defend calcium serum in normal range, and the extract of Cissus quadrangularis can prevent osteoporosis.

Keyword :

Cissus quadrangularis, calcium serum, ovariectomy, osteoporosis,


References :

  1. Firman, I, (2005). Gambaran Histopatologik Tulang Femur Tikus Putih (Rattus Norvegicus) Betina Pasca Ovariohisterektomi Dengan Suplemen Kalsium Karbonat Dosis Tinggi. Surabaya : Skripsi FKH Unair
  2. Raisz, L.G. and A. Johannessons, (1984). Pathogenesis, Prevention and Therapy of Osteoporosis. New York : Journal of Med, 15:267 – 278
  3. Mario Chiechi, L, and Micheli, L., (2005). Utility Of Dietary Phytoestrogens In Preventing Postmenopausal Osteoporosis. Department Of Ostetrics and Gynecology. University of Bari. Italy : J. New Century Health Publishers. LLC
  4. Potu, B.K., M.S. Rao, G.K. Nampurath, M.R. Chamallamudi, S.R. Nayak, H. Thomas, (2009). Anti-osteoporotic Activity of the Petroleum Ether Extract of Cissus quadrangularis Linn. in Ovariectomized Wistar Rats. Kuwait : Faculty of Medicine. Kuwait University


   


Archive Article

Cover Media Content

Volume : 2 / No. : 2 / Pub. : 2014-01
  1. The root of the plant cikal tulang (cissus quadrangularis) extract in ovariectomized rats (rattus norvegicus) as an animal model of osteoporosis on levels of blood calcium
  2. Case study : mastitis in cat
  3. Babesiosis in dogs in veterinary teaching hospital airlangga university