UNIVERSITAS AIRLANGGA



Detail Article

Jurnal Oftalmologi Indonesia

ISSN 1693-2587

Vol. 5 / No. 3 / Published : 2007-12

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Original Article :

C y t o k i n e s

Author :

  1. Admadi Soeroso*1
  1. Bag./Lab. Ilmu Penyakit Mata Fakultas Kedokteran Universitas Negeri Sebelas Maret / RSUD Dr. Moewardi, Jl. Kolonel Sutanto No. 132 Surakarta

Abstract :

Many critical interactions among cells of the immune system are controlled by soluble mediators called cytokines. These cytokines are a diverse group of intercellular signaling peptides and glycoproteins with low molecular weights and most of them are genetically and structurally unrelated to one another. Several hundred have been identified to date. Each is secreted by particular cell types in response to a variety stimuli and produces characteristic effects on the growth, mobility, differentiation, or function of target cells. Collectivelly, they regulate not only immune and inflammatory responses but also wound healing, hematopoiesis, angiogenesis, and many other biologic processes. They are extremely potent compound that act at slight concentrations by binding to specific surface receptors on target cells. Unlike endocrine hormones, they are not produced by specialized glands and secreted into the circulation, but rather are produced locally by a variety of tissues and cells. Only a few cytokines, such as transforming growth factor beta, erythropoietin, stem cell factor (SCF), monocyte colony-stimulating factor (M-CSF), are normally present in detectable amounts in the blood and are able to influence distant target cells. Most other cytokines, unless produced in excess, act only locally over short distances, in either a paracrine manner (ie, on adjacent cells) or an autocrine manner (ie, on producing cell itself).

Keyword :

cytokines ,


References :

I Handoyo,(2003) Pengantar imunoasai dasar, cetakan pertama Surabaya Indonesia : Airlangga University Press





Archive Article

Cover Media Content

Volume : 5 / No. : 3 / Pub. : 2008-12
  1. C Y T O K I N E S
  2. Skin Flap Pada Kelopak Mata
  3. Fitting Lensa Kontak Rigid Gas Permeable (rgp)
  4. Teknik Pembedahan Rekonstruksi Pasca Eksisi Tumor Ganas Kelopak Mata
  5. Diplopia Binokuler Akibat Paresis N Iii, Iv Dan Vi Di Rs Mata Dr. Yap Yogyakarta
  6. Comparison Of P53 Expression In Hpv(+) And Hpv(-) In Conjunctival And Eyelid Squamous Neoplasia
  7. The Comparison Of Tetracycline And Doxycycline Treatment On Corneal Epithelial Wound Healing In The Rabbit Acid-burn Model
  8. Dandy Walker Syndrome In 7 Month-old Boy
  9. Combination Of Cutler -beard Flap,v-y Glabellar Flap And Direct Closure For Large Resection Upper Eyelid And Medial Canthus
  10. Limbal Stem Cell Transplantation In Limbal Stem Cell Deficiency After Steven Johnson Syndrome
  11. Hypoglobus And Ptosis Reconstruction After Lacrimal Benign Mesenchymal Tumor Excision
  12. Association Between Refractive Changes And Blood Glucose Changes In Diabetic Mellitus Type 2 Patient
  13. Management Of The Complication After Silicone Fluid Injection At Facial And Eyelid Region
  14. The Difference Of Epidermal Growth Factor Concentration Between Fresh And Freeze-dried Amniotic Membranes
  15. Sindroma Laurence-moon-bardet-biedl
  16. Bilateral Orbital Apex Syndrome
  17. Clinical Difference Between Autograft Post Operated Pterygium Using Fibrin Glue And Polyglycolic Acid 10-0 Suture

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