Jurnal Oftalmologi Indonesia
ISSN 1693-2587
Vol. 7 / No. 2 / Published : 2009-12
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Original Article :
The comparison of active and total transforming growth factor-e2 concentration on fresh and cryopreservation amnion membrane
Author :
- Dicky Hermawan*1
- Rowena G. Hoesin*2
- Gatut Suhendro*3
- Department of Ophthalmology, Faculty of Medicine Airlangga University/Dr. Soetomo General Hospital, Surabaya
Abstract :
The aim of this study is to find the difference of TGF-E2 level in fresh amnion membrane and preserved amnion membrane usingcryopreservation method. This study used one group pretest-posttest design and statistical analysis was performed using WilcoxonSigned-Rank test if the samples had no normal distribution with level of significance ofD= 0.05. Eleven samples of amnion membranewere used to measure active TGF-E2 level before and after preservation using cryopreservation method, and 13 samples of amnionmembrane were used to measure total TGF-E2 level before and after preservation using cryopreservation method. TGF-E2 level infresh amnion membrane was higher than that in amnion membrane preserved using cryopreservation method. There is no significantreduction of TGF-E2 level in amnion membrane preserved using cryopreservation method.
Keyword :
TGF-E2, fresh amniotic membrane, cryopreservation,
References :
Royal College,(2008) Amniotic membrane transplantation in ophthalmology - : Royal College of Ophthalmologists Guidelines. http://www.mrcophth.com
Imanishi J., Kamiyama K., Iguchi I., Kita M., Sotozono C., Kinoshita S,(2000) Growth factors: Importance in Wound Healing and Maintenance of Transparency of the Cornea - : Progress in retinal and eye research
Virender S., Burman S., Tejwani S. Mahesh S.P., Murthy R,(2007) Amniotic membrane transplantation: A review of current indications in the management of ophthalmic disorders - : Current Ophthalmology
Archive Article
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