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Jurnal Penelitian Medika Eksakta

ISSN 1411-6626

Vol. 4 / No. 1 / Published : 2003-04

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Original Article :

The prevantion effect of the endothelial cell by aqueous extract of garlic (allium sativum linn) on hypercholesterolemia

Author :

      Abstract :

      The aim of this study was to prove that aqueous extract of garlic can prevent endothelial cell damage on hypercholesterolemia. This study used Completely Randomised Design. Thirty five male rabbits (1,5 – 2 kg BW) were used in the experiment. Rabbits were divided into five groups of seven each and were treated as follows: Group A AS negative control were given aquadest 5 ml/kg BW/day for 4 weeks; Group B AS positive control were given aquadest 5 ml/kg BW/day + cholesterol 0,2 g /kg BW/day for 4 weeks; Group C AS positive control were given cholesterol 0,2 g /kg BW/day + aqueous extract of garlic 25%, 5 ml/kg BW/day for 4 weeks. Group D AS were given cholesterol 0,2 g /kg BW/day + aqueous extract of garlic 50%, 5 ml/kg BW/day for 4 weeks. Group E AS were given cholesterol 0,2g/kg BW/day + aqueous extract of garlic 75%, 5 ml/kg BW/day for 4 weeks. The result showed that aqueous extract of garlic decresed circulating endhotel (p0,1). Increasing dose of aqueous extract of garlic could not decrease (p>0,1) circulating endothel and MDA. It is recommended that administration aqueous extract of garlic over 4 weeks.

      Keyword :

      Endothelial Cell, Garlic Extract, Hypercholesterolemia,


      References :



           


        Archive Article

        Cover Media Content

        Volume : 4 / No. : 1 / Pub. : 2003-04
        1. The Effect Of Java Ginseng Root Exstrac To Spermatogenesis By Induced Of 2-methoxyethanol
        2. Analysis Of Diffusion Coefficient For Ternary System From Reconstruction Of Off- Axis Hologram With Computer Simulation Program
        3. Efectivity Of Polyclonal Antibody Of Pmsg To Produce Oocyte And Embryo Of Mice
        4. The Prevantion Effect Of The Endothelial Cell By Aqueous Extract Of Garlic (allium Sativum Linn) On Hypercholesterolemia
        5. The Role Of Garlic (allium Sativum) Antioxidant As Hepatoprotector
        6. The Antifertility Activity Of Quercetin Pentaasetat In Male Mice
        7. Effect Of Polyphenol Fraction Of Gendarussa Vulgaris Nees On Decrease Hyaluronidase Activity By In Vitro Fertilization Test
        8. Saliva Buffer Effectivity Difference Between Low Caries And High Caries Patients Before And After Restorations