Jurnal Respirasi
ISSN 2407-0830
Vol. 1 / No. 3 / Published : 2015-09
Order : 2, and page :81 - 87
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Original Article :
Tb mdr primer dengan limfadenitis tb pada wanita sle
Author :
- Ika Yunita Sari*1
- Daniel Maranatha*2
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
Abstract :
Background. Primary resistance is the resistance that occurs in patients who have never received treatment OAT or had ever receivedtreatment OAT is less than 1 month. The incidence of primary MDR in Central Java in 2006 2.07%. Extrapulmonary TB about 15-20%of all cases of TB, and TB lymphadenitis is the highest form (35% of all extrapulmonary TB). Patients with decreased immune systems(SLE) can increase the incidence of TB. Research in Spain get 6x higher TB incidence in patients with SLE. Case. We present the caseof 19 year old woman SLE who received treatment for 11 months whose came with shortness of breath and chronic cough since 2 monthprior to admission. In physical examination we found right and left submandibula lymphonodi enlargement as solid, slightly mobilenodule with diameter 3 cm. Chest X ray showed lung inflammation which suspicion of specific process and minimal left pleural effusion,and concluded as pulmonary TB. FNAB confirmed lymphadenitis TB with granulomatous inflammation. One of AFB result is positiveand Gene Xpert is M.tb positive with rifampicin resistant that make this patient categorized as primary MDR TB with lymphadenitisTB. This patient received Pirazinamid 1500 mg, Ethambutol 800 mg, Kanamicin 750 mg, Levofloxacin 750 mg, Ethionamide 500 mg,Cicloserin 500 mg, and B6 100 mg. Conclusion. MDR TB in general occur in patients with a history of OAT previous TB (MDR TBsecondary). Primary MDR TB with lymphadenitis tb is a rare case, but can occur on the condition that decreases the immune system,one of SLE. This involves multiple immune disorders caused by the use of long-term immunosuppressive therapy.
Keyword :
primary resistance , lymphadenitis TB, SLE,
References :
Perhimpunan Dokter Paru Indonesia,(2011) Tuberculosis: pedoman diagnosis dan penatalaksanaan di Indonesia. 1–64. : PDPI
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Volume : 1 / No. : 3 / Pub. : 2015-09 |
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