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Majalah Farmasi Airlangga (Airlangga Journal of Pharmacy)

ISSN 0852-1050

Vol. 5 / No. 3 / Published : 2005-12

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Original Article :

Aktivitas antimalaria ekstrak diklorometana kulit batang artocarpus champeden pada kultur plasmodium falciparum

Author :

  1. Nuri*1
  2. Yoes Prijatna Dachlan*2
  3. Noor Cholies Zaini*3
  4. Mulja Hadi Santosa*4
  5. Aty Widyawaruyanti*5
  6. Sjafruddin*6
  1. Bagian Ilmu Bahan Alam Program Studi Farmasi Universitas Jember
  2. Tropical Disease Centre Universitas Airlangga
  3. akultas Farmasi Universitas Airlangga
  4. Fakultas Farmasi Universitas Airlangga
  5. Fakultas Farmasi Universitas Airlangga
  6. Lembaga Biologi Molekuler Eijkman Jakarta

Abstract :

Artocarpus champeden has been used traditionally in Irian Jaya for the treatment of malaria. Scientific validation of this utilization was not previously made. The antimalarial activity of dichlorometane extract of A. champeden stem bark was tested against Plasmodium falciparum chloroquin-resistant strain (G2300) and chloroquin-sensitive strain (3D7) in vitro. The result showed that the dichlorometane extract of A. champeden stem bark inhibited the growth of P. falciparum chloroquin-resistant strain and chloroquin-sensitive strain with IC50 value 0,14432 μg/ml and 0,93633 μg/ml respectively.

Keyword :

Artocarpus champeden, antimalarial, Plasmodium falciparum,


References :

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Archive Article

Cover Media Content

Volume : 5 / No. : 3 / Pub. : 2008-01
  1. Uji efektifitas sediaan gel antiseptik tangan yang mengandung etanol dan triklosan
  2. Pengembangan formula sediaan gel antiseptik tangan ekstrak daun sirih (piper betle linn)
  3. Pengaruh posisi gugus metoksi para dan meta terhadap hasil sintesis asam para-metoksisinamat dan asam meta-metoksisinamat
  4. Aktivitas antimalaria ekstrak metanol, fraksi dan isolat-isolat dari kulit batang cempedak (artocarpus champeden, spreng.)
  5. Aktivitas antimalaria ekstrak diklorometana kulit batang artocarpus champeden pada kultur plasmodium falciparum
  6. Uji toksisitas akut dan subakut ekstrak etanol dan ekstrak air kulit batang artocarpus champeden spreng dengan parameter histopatologi hati mencit
  7. Pengaruh ekstrak etanol dan ekstrak air kulit batang artocarpus champeden spreng terhadap kadar enzim sgpt dan sgot mencit.