UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 8 / No. 1 / Published : 2008-10

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Original Article :

Pemulihan kadar testosteron dengan β - sitosterol

Author :

  1. Dwi Winarni*1
  2. Ismudiono*2
  3. Ami Soewandi*3
  4. Win Darmanto*4
  1. Departemen Biologi, Fakultas Sains dan Teknologi Universitas Airlangga Surabaya
  2. Departemen Fisiologi Reproduksi, Fakultas Kedokteran Hewan Unair Surabaya
  3. Departemen Kimia, Fakultas Sains dan Teknologi Unair Surabaya
  4. Departemen Biologi, Fakultas Sains dan Teknologi Universitas Airlangga Surabaya

Abstract :

The objective of this research was to know the effect of β-sitosterol on testosterone level recovery. This research used 36 adult male mice (Mus musculus) strain BALB-C that had low total testosterone level. Testoterone level was decreased by ethynilestradiol (EE2) pretreatment 70.0 µg/kg bw/day for 9 days. After that, pretreatment was stopped for 18 mice (group without EE2), and still given for the other (group with EE2). Each group was divided into 2 subgroups. It was administered by β-sitosterol 8.1 µg/kg bw/day (Ps) and control without β-sitosterol (Po). Further, each subgroup was divided into sub-subgroups that were administered treatment for 9, 18 and 27 days. The level of serum total testosterone level was measured by radioimmunoassay. The result of this research revealed that β-sitosterol shortened the recovery time of testosterone level, but it depended on testosterone level that would be recovered

Keyword :

Recovery, testosterone level, β - sitosterol,


References :





Archive Article

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