UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 8 / No. 1 / Published : 2008-10

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Original Article :

Potensi propolis dalam mencegah penurunan jumlah sel leydig dan sertoli akibat latihan fisik berat pada tikus putih

Author :

  1. Hairrudin*1
  2. Dina Helianti*2
  3. Maulidina Fitria Ning Tyas*3
  1. Laboratorium Biokimia Fakultas Kedokteran Universitas Jember
    Jl. Kalimantan 37 Kampus Bumi Tegalboto Jember
  2. Staf pengajar Laboratorium Histologi Fakultas Kedokteran Universitas Jember
  3. Mahasiswa Fakultas Kedokteran Universitas Jember

Abstract :

The purpose of the research was to know the effect of propolis to prevent decrease of leydig and sertoli cell induce by severe physical exercise in rats. This research was used post test only group design. The sample divided into four groups, every groups consist of eight rats: K1, negative control; K2, positive control, with propolis; P1, severe physical exercise without propolis; P2 severe physical exercise with propolis 64 mg/KgBW. After 30 days the rats was sacrificed and the testis tissue was stained with HE. The results show number of leydig cell and sertoli cell respectively in group K1( 203,38; 12,301,77), K2 (192,95; 12,501,92), P1 (11,932,21; 9,052,05), P2 (17,482,74; 11,431,90). The result shown that severe physical exercise increase ROS cause by increase the oxygen consumption and metabolic rate that prevent by many kind antioxidant in the propolis. Take together from this result we conclude that propolis can prevent decrease of leydig.

Keyword :

Severe physical exercise, propolis, ROS, leydig cell, sertoli cell,


References :





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