UNIVERSITAS AIRLANGGA



Detail Article

Majalah Ilmu Faal Indonesia

ISSN 0215-1995

Vol. 11 / No. 2 / Published : 2016-09

Order : 7, and page :84 - 90

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Original Article :

Supplementation of saturated fatty acid, mono unsaturated fatty acid, and poly unsaturated fatty acid: triglyceride comparison study on white rat (rattus norvegicus)

Author :

  1. Christian Reza Wibowo*1
  2. Harlina*2
  3. Raden Argarini*3
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

Introduction: Fatty acids are well known for its decaying effects among people nowadays. In fact, there are several fatty acids which have the ability to repair the lipid profile in blood. Purpose: The aim of this research was to find out the comparison of saturated fatty acids, mono unsatturated fatty acids, and poly unsatturated fatty acids supplemented in white rats (Rattus norvegicus). Twenty four mice, divided in 4 group, were given three different oilswhich contain different fatty acids for three weeks. Group K0 were given aquades as a placebo (control group). Group K1 was given a virgin coconut oil, group K2 was given a sunflower oil, and group K3 was given an olive oil. Every groups were given the same amount of dosage which was 0,5gr/200grBB. The blood were collected using syringe intracardially. The blood samples were checked to find out the amount of lipid profile solved. The data was analyzed using One Way ANOVA design with SPSS 18 software. The LDL, HDL, and total cholesterol in K1 (p=0,374), K2 (p=0,975), and K3 (p=0,761) were not decreased nor increased significantly. In the other hand, there were significant differences (p<0,05) found in every groups in terms of triglyceride with p value = 0,004. Olive oil (K3) have successfully decreased triglyceride significantly compared to K1 (p=0,006), and K2 (p=0,002). Meanwhile, virgin coconut oil had also made significant differences which was higher compared to K0 (p=0,021) and K3 (p=0,006). Least, sunflower oil had made significant differences which was also higher compared to K0 (p=0,008) and K3 (p=0,002). In conclusion: olive oil were able to repair the lipid profile which in this case triglyceride while sunflower oil and virgin coconut oil were increasing the triglyceride significantly.

Keyword :

lipid profile, sunflower oil, olive oil, virgin coconut oil,


References :

Bach AC, VK Babayan,(1982) Medium-Chain Triglycerides:An Update 36:950-962 : Am J Clin Nutr

Blaton, V, dan Hollez, D,(1986) Effects of Dietary Fatty Acids On The Composition Of Serum Lipoproteins HAL: 141 : Nutritional Effects onCholesterol Metabolism.Beynen, A.C. (ed)

Enig, M,(1999) Coconut Oil: Atherogenic or not? (What therefore causes atherosclerosis) 31:97-104 : Philip J Cardiol





Archive Article

Cover Media Content

Volume : 11 / No. : 2 / Pub. : 2016-09
  1. A Function Discriminate The Risk Of Type 2 Diabetes Among Indonesian Obese Characteristics
  2. Dynamic Eccentric Exercise Improve Glut-1 Expression On Calf Muscle Of Diabetic Mice Models
  3. Effects Of Tumeric Ethanol Extract (curcuma Domestica Val) To Prevent Ulcus Pepticum Which Induced By Histamin
  4. Effect Of Caffeine On Endurance Duration Of Student Using Graded Exercise Test
  5. Effects Of Glutathione Protection Against Erythrocytes Post Submaximal Physical Exercise On Rat (rattus Norvegicus) Males
  6. Administration Of Sembukan’s Leaves Extract Improve Blood Glucose Level In Diabetes Mellitus Animal Model
  7. Supplementation Of Saturated Fatty Acid, Mono Unsaturated Fatty Acid, And Poly Unsaturated Fatty Acid: Triglyceride Comparison Study On White Rat (rattus Norvegicus)
  8. Comparison Of Lumbar Flexibility And Hamstring Muscles Shortening In Full Day And Non Full Day Students
  9. Correlation Between Body Mass Index With Physical Fitness Student Of Airlangga University
  10. The Effects Of Interval Training On Slowing Of Weight Gain And Lowering Lee Index Scoring In An Obese Rats Model

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