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Media Kedokteran Hewan

ISSN 2015-8930

Vol. 20 / No. 1 / Published : 2004-01

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Original Article :

Efects of liquid waste product from leather tanning factory on the liver histopatological changes and sgot - sgpt levels of albino mice (rattus norvegicus)

Author :

  1. Ajik Azmijah*1
  2. Thomas V. Widiyatno*2
  3. Roesno Darsono*3
  4. Hani Plumeriastuti*4
  5. Laksmi Sulmartiwi.*5
  1. Lab. Patologi Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga, Surabaya
  2. Lab. Patologi Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga, Surabaya
  3. Lab. Patologi Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga, Surabaya
  4. Lab. Patologi Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga, Surabaya
  5. Lab. Patologi Veteriner, Fakultas Kedokteran Hewan, Universitas Airlangga, Surabaya

Abstract :

The aims of the study was to measure the effect of the liquid waste product of leather tannine factory against the liver histopathological changes of albino mice and the SGOT and SPGT level in the blood serum. The waste product contained of some organic compound and heavy metal materials. Fourty five mice were divided into 3 groups. Two groups were given waste product ( treated group ) and the other was taken as a control group. The result did not show any differences between treated and control group in SGOT- SGPT level. Histopathological examination, however , revealed slight changes such as congestion, fatty change as well as centrolobulair degeneration.

Keyword :

liquid waste, leather tanning factory, liver histhopatological change, SGOT-SGPT level, Rattus norvegicus.,


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