Majalah Obstetri & Ginekologi
ISSN 0854-0381
Vol. 20 / No. 1 / Published : 2012-01
Order : 3, and page :14 - 17
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Original Article :
Difference of par-1 expressions on new zealand rabbit following surabaya method uterine compression suture after cesarean delivery
Author :
- Alia Shahnaz*1
- Agus Sulistyono*2
- Widjiati*3
- Mahasiswa Fakultas Kedokteran
- Dosen Fakultas Kedokteran
- Dosen Fakultas Kedokteran Hewan
Abstract :
Surabaya uterine compression suture is a modification from B-Lynch procedure as one of compression technique for the management of hemorrhage due to uterine atony. This study observed the expression numbers of PAR-1 in New Zealand rabbit uterus at half hours and two hours after Surabaya compression. Twenty-one adult female New Zealand rabbits were induced for pregnancy. All were given birth by cesarean section. Population was divided into two groups one group showed as exposure group which underwent uterine compression suture using Surabaya method and the other side as control group with no exposure to uterine compression suture. Histopathology specimen was taken from study and control group and count on the number of PAR-1 expressions which after observed at half hour and two hours. Statistical analysis using paired T test shows increase on expressions of PAR-1 at study group compare to control group (p<0,05) on half hour and two hours observations. In conclusion, mechanic stimuli using Surabaya uterus compression produces significant increase in the expressions of PAR-1 after 30 minutes and two hours. (MOG 2012;20:14-17)
Keyword :
Surabaya method compression suture, PAR-1 expression, post partum hemorrhagic , -, -,
References :
Anderson JM and Etches D,(2007) Prevention and management of postpartum hemorrhage - : American academy of family physicians
B-Lynch C,(2006) Conservative Surgical management - : In A Text Book of Postpartum Hemorrhage 1st ed
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Volume : 20 / No. : 1 / Pub. : 2012-01 |
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