UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 4 / No. 1 / Published : 2015-04

Order : 1, and page :1 - 4

Related with : Scholar   Yahoo!   Bing

Original Article :

Boraks mengakibatkan penurunan jumlah sel spermatogonium dan sel sertoli pada gambaran histopatologi testis tikus putih (rattus norvegicus)

Author :

  1. Izzatul Ulfana*1
  2. Roesno Darsono*2
  3. Sri Mulyati*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of this study was to evaluate the histopathological changes in testis of wistar rats after giving borax using different subchronic toxicity doses. The research has been done on July, 9th 2013-September, 29th 2013 at Department of Pathology Veterinary, Faculty of Veterinary Medicine, Universitas Airlangga. Twenty male rats (Rattus norvegicus strain Wistar) 45 days old with body weight 200 g were used. These animals were divided into four groups (P0, P1, P2, and P3). P0 were treated with sterile aquadest 0,5 ml/rats/day, P1 were treated with borax 19 mg/rats/day, P2 were treated with borax 26 mg/rats/day, and P3 were treated with borax 37 mg/rats/day. This research has been conducted for 14 days to determine the toxic effects of borax on the testis. The data were compared using ANOVA test and Duncan  test. Statistical comparisons were performed using SPSS versi 20.0 for windows. The result showed that borax significantly caused decrease number of spermatogonium cells and sertoli cells on testical histopathology (p<0,05).

Keyword :

borax, disodium tetraborate decahydrate, testical histopathology,


References :

Chapin RE, Ku WW, Wine. RN, Glade BC.,(1994) Testicular Toxicity of Boric Acid Relationship of Doseto Lesion Development And Recovery in the F 344 Rat. 7 (4); 305-319 : Repro. Toxicol.

Nielsen, FH.,(1994) Biochemical and physiologic consequences of boron deprivation in humans. 102(7):59-63. : Environ Health Perspect





Archive Article

Cover Media Content

Volume : 4 / No. : 1 / Pub. : 2015-04
  1. Boraks Mengakibatkan Penurunan Jumlah Sel Spermatogonium Dan Sel Sertoli Pada Gambaran Histopatologi Testis Tikus Putih (rattus Norvegicus)
  2. Kadar Progesteron Serum Domba Ekor Gemuk Sebelum Pemasangan Dan Sesudah Pencabutan Implan Progesteron Subkutan
  3. Pemberian Injeksi Kombinasi Hormon Pmsg Dan Hcg Terhadap Waktu Timbulnya Birahi Pada Sapi Madura Di Desa Sembilangan Kecamatan Bangkalan Kabupaten Bangkalan
  4. Pengaruh Pemberian Infusa Kulit Manggis (garcinia Mangostana L.) Terhadap Peningkatan Persentase Kapasitasi Spermatozoa Tikus Putih (rattus Norvegicus)
  5. Pengaruh Pemberian Infusa Kulit Manggis (garcinia Mangostana L.) Terhadap Motilitas, Viabilitas Dan Integritas Membran Spermatozoa Tikus Putih (rattus Norvegicus)
  6. Perubahan Histopatologi Jaringan Interstitial Testis Tikus Putih (rattus Norvegicus) Yang Dipapar Boraks (na2b4o7.10h2o)
  7. Waktu Inseminasi Buatan Pada Sapi Perah Yang Digertak Birahi Dengan Hormon Prostaglandin F2α Dan Hormon Gonadotropin
  8. Isolasi Dan Karakterisasi Fertility Associated Antigen (faa) Dalam Membran Spermatozoa Sebagai Bahan Aktif Kesuburan Spermatozoa Sapi
  9. Perbedaan Non Return Rate (nrr) Hari Ke 21 Dan Conception Rate (cr) Hari Ke 75 Sapi Perah Yang Disinkronisasi Birahi Menggunakan Prostaglandin F2α (pgf2α) Dengan Gonadotropin (kombinasi Pmsg Dan Hcg)
  10. Pengujian Kualitas Semen Segar Kambing Gembrong Untuk Proses Pembekuan Di Teaching Farm
  11. Pengaruh Waktu Equilibrasi Terhadap Motilitas Dan Viabilitas Spermatozoa Kambing Gembrong Post Thawing Dalam Pengencer Skim Kuning Telur
  12. Nilai Bod (biochemical Oxygen Deman) Dan Cod (chemical Oxygen Deman) Air Kolam Dan Limbah Usaha Perikanan Yang Menggunakan Kotoran Bebek Sebagai Media Budidaya Ikan Lele
  13. Pemeriksaan Kadar Hormon Estrogen Sebagai Indikator Diagnostik Adanya Kebuntingan Dini Pada Kuda Poni
  14. Pengaruh Berbagai Konsentrasi Kuning Telur Itik Dalam Susu Skim Sebagai Pengencer Semen Domba Ekor Gemuk Terhadap Motilitas, Viabilitas Dan Keutuhan Membran Plasma Spermatozoa Before Freezing

Information OVOZOA