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OVOZOA

ISSN 2302-6464

Vol. 7 / No. 2 / Published : 2018-10

TOC : 12, and page :143 - 148

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Original Article :

Pengaruh pemberian insulin-like growth factor-i (igf-i) dari serum kuda crossbreed bunting terhadap ketebalan endometrium mencit (mus musculus)

Author :

  1. Dyah Ayu R.R.Y*1
  2. Dr. Sri Mulyati, drh., M.Kes.*2
  3. Roesno Darsono, drh., M.Vet.*3
  4. Prof. Dr. Imam Mustofa., drh., M.Kes*4
  5. Arimbi,drh., M.Kes.*5
  6. Dr. Widjiati, drh., MSi.*6
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan
  4. Dosen Fakultas Kedokteran Hewan
  5. Dosen Fakultas Kedokteran Hewan
  6. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of the research was to know  the effect of Insulin-Like Growth Factor-I (IGF-I) derived from pregnant crossbreed mare serum (PMS) on endometrium thickness of mice (Mus musculus). The subject of this research were 35 female mice. The research was arranged by Completely Randomized Design (CRD) with seven treatment and five replications. The treatment were P0 = 10 ng/ml of physiological NaCl, P11 = 10 ng/ml of IGF-I PMS, P12 = 20 ng/ml of IGF-I PMS, P13 = 40 ng/ml of IGF-I PMS, P21 = 10 ng/ml of IGF-I recombinant mouse, P22 = 20 ng/ml of IGF-I recombinant mouse, and P23 = 40 ng/ml of IGF-I recombinant mouse. Observed variables include histopatological endometrium thickness of mice. The data were analyzed by Analysis of Variance (ANOVA), followed by HSD (Honestly Significant Difference) test. The data was also be analyzed using General Linear Model Univarieted to see the comparison between IGF-I PMS and recombinant mouse. The result showed that the addition of IGF-I PMS did not significantly affect (p>0,05) on endometrium thickness of mice . It showed that did not significantly difference (p>0,05) between the effect of IGF-I PMS and IGF-I recombinant mouse against the endometrium thickness of mice.

Keyword :

IGF-I, IGF-I pregnant crossbreed mare serum, endometrium thickness, Mus musculus .,


References :

  1. Inoue, Ayako., Takeuchi, Sakae, and T. Sumio. , (2005). Insulin-Like Growth Factor-I Stimulated DNA Replication in Mouse Endometrial Stroma Cells.. 51: 3. : Journal of Reproduction and Development.
  2. Murphy, L.J., Ghahary A. , (1990). Uterine Insulin-Like Growth Factor-1: Regulation of Expression and Its Role in Estrogen-Induced Uterine Proliferation. . 11(3): 443-453. : Endocrinology Rev.
  3. Peters, A.R. , (1985). Hormonal Control of Bovine Oestrus Cycle I.. 47: 1-114 : J. Reprod. Fertil.
  4. Roche, J.F. , (1998). Controlls Of Foliculogenesis. . 49:457-467 : J Theriology.


   


Archive Article

Cover Media Content

Volume : 7 / No. : 2 / Pub. : 2018-10
  1. Penambahan l – arginin dalam pengencer tris kuning telur setelah ekuilibrasi 2 jam terhadap motilitas dan membran plasma utuh spermatozoa domba sapudi
  2. Conception rate dan service per conception pada sapi perah akseptor inseminasi buatan di kud argopuro kecamatan krucil kabupaten probolinggo
  3. Profil protein tirosin kinase dalam seminal plasma domba merino dengan teknik sodium dodecyl sulphate polyacrilamide gel electrophoresis
  4. Kualitas motilitas dan viabilitas spermatozoa dari semen afkir sapi limousin pada pengencer susu skim kuning telur sitrat dengan penambahan berbagai kadar glukosa
  5. Kasus distokia pada sapi potong di kecamatan kunir kabupaten lumajang tahun 2015 dan 2016
  6. Pengaruh pemberian insulin-like growth factor-i (igf-i) dari serum kuda crossbreed bunting terhadap folikulogenesis mencit (mus musculus)
  7. Conception rate dan service per conception pada sapi peranakan limousin dan sapi peranakan ongole hasil ib di kecamatan pilangkenceng kabupaten madiun
  8. Pengaruh penembakan laserpunktur pada titik reproduksi itik mojosari (anas platyrhynchos) jantan terhadap jumlah sel spermatogonium dan diameter tubulus seminiferus
  9. Efek penembakan laserpunktur pada titik ova bebek mojosari jantan terhadap jumlah sel sertoli dan leydig
  10. Uji berbagai alat deteksi birahi terhadap angka kebuntingan pada sapi perah di koperasi tunas setia baru kabupaten pasuruan
  11. Pengaruh lama waktu penghitungan straw dan posisi jarak straw diatas permukaan nitrogen cair terhadap motilitas dan viabilitas semen beku sapi madura post thawing
  12. Pengaruh pemberian insulin-like growth factor-i (igf-i) dari serum kuda crossbreed bunting terhadap ketebalan endometrium mencit (mus musculus)
  13. Pengaruh jarak dan lama waktu proses penghitungan straw sebelum distribusi terhadap kualitas semen beku sapi simental post thawing