UNIVERSITAS AIRLANGGA



Detail Article

OVOZOA

ISSN 2302-6464

Vol. 7 / No. 1 / Published : 2018-04

Order : 8, and page :37 - 41

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Original Article :

Potensi ekstrak etanol seledri (apium graveolens) terhadap diameter tubulus seminiferus dan jumlah sel spermatogenik mencit (mus musculus)

Author :

  1. Ricky Hadinata Alamsyah*1
  2. Dr. Eka P. Hestianah, drh., M.Kes.*2
  3. Dr. Tutik Juniastuti, drh., M.Kes.*3
  4. Prof. Dr. Wurlina, drh., M.S.*4
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan
  4. Dosen Fakultas Kedokteran Hewan

Abstract :

This study was aimed at evaluating the potential effect of ethalnolic extract of celery (Apium graveolens) on the diameter of seminiferous tubules and the quantity of spermatogenic cells in male mice (Mus musculus). The method used to make the extract celery (Apium graveolens) in this study was maceration with ethanol. Twenty male mice (Mus musculus) were adapted for one week and divided into four groups using simple random sample system; P0 (negative control) was given solvent of CMC Na 0,5%, P1 was given 49,53 mg/kg body weight of ethanolic extract of celery (Apium graveolens), P2 was given 59,5 mg/kg body weight of ethanolic extract of celery (Apium graveolens), P3 was given 67,06 mg/kg body weight of ethanolic extract of celery (Apium graveolens). The treatsments were administered by oral gavage for fourteen consencutive days. The 15nd day, mice (Mus musculus) terminated by euthanasia using chloroform. The diameter of seminiferous tubules was observed microscopically at 100x magnification and assisted by Image Raster. The quantity of spermatogenic cells were observed microscopically at 400x magnification. The data were analyzed by Analysis of Variance Test and continued by Duncan’s Multiple Range Test. The result showed that ethanolic extract of celery (Apium graveoles) could not decrease the diameter of seminiferous tubules and could not decrease the quantity of spermatogenic cells significantly

Keyword :

Apium graveolens, Seminiferus Tubules, Spermatogenic cells, male mice,


References :

  1. Al-Sanabra, O.M.F., E.A. Qunaibi, T.A. Aburjai, F.A. Al-Qaadan, M.S. Shomaf and A.M. Disi. , (2013). Antifertility Activity of Ethanolic Seed Extract of Celery (Apium graveolens L.) in Male Albino Rats. . 6(1): 1-10. : Jordan Journal of Pharmaceutical Sciences.
  2. Garg, S., G.P. Talwar, S.N. Upadhyay., (1998). Immunocontraceptive activity guided fraction and characterization of active costituents of neem (Azadirachta indica) seed extracts.. 60(3): 235-246. : J. Ethnopharmacol.
  3. Hiremath, S.P., K. Rudresh, S. Badani, S.B. Patil, S.R. Patil., (1998). Post-coital Antifertility Activity of Acalypha indica L.. 67(3): 253-258. : J. Ethnopharmacol.
  4. Hiremath, S.P., S. Badani, S.K. Hunasagatta, S.B. Patil., (2000). Antifertility and Hormonal Properties of Flavones of Striga Orobanchioides.. 391(1-2): 193-197. : Eur J. Pharmacol.
  5. Joshi, S.C., A. Sharma and M. Chaturvedi., (2011). Antifertility Potential of Some Medical Plants in Males: an Overview.. 3(5): 204-217. : Internaltional Journal of Pharmacy and Pharmaceutical Sciences.
  6. Modaresi, M., G. Ghalamkari and A. Jalalizand., (2012). The Effect of Celery (Apium graveolens) Extract on the Reproductive Hormones in Male Mice.. 4: 99-104. : APCBEE Procedia.




Archive Article

Cover Media Content

Volume : 7 / No. : 1 / Pub. : 2018-04
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  2. Efisiensi reproduksi sapi perah di kecamatan cendana kabupaten enrekang sulawesi selatan
  3. Pengaruh penambahan l-arginin pada media pengencer skim-kuning telur terhadap membran plasma dan tudung akrosom spermatozoa domba merino post thawing
  4. Pengaruh pemberian beras merah (oryza nivara) dibandingkan beras putih (oryza sativa) terhadap jumlah anak dan bobot lahir anak mencit (mus musculus) sekelahiran yang hidup
  5. Analisis kadar kalsium (ca) dan fosfor (p) serum sapi perah penderita milk fever di wilayah kerja kpsp setia kawan kecamatan tutur pasuruan
  6. Pengaruh substitusi sari buah tomat (lycopersicon esculentum mill.) pada media pengencer kuning telur sitrat terhadap motilitas, viabilitas dan membran plasma utuh spermatozoa domba ekor gemuk pada suhu penyimpanan 3-5º c
  7. Pengaruh perbedaan waktu inseminasi buatan terhadap angka kebuntingan domba ekor gemuk yang disinkronisasi dengan prostaglandin f2α
  8. Potensi ekstrak etanol seledri (apium graveolens) terhadap diameter tubulus seminiferus dan jumlah sel spermatogenik mencit (mus musculus)
  9. Penambahan sari air laut (nigarin) dalam pengencer skim kuning telur terhadap viabilitas dan motilitas spermatozoa sapi limousin post thawing
  10. Efek pemberian l-arginine secara oral pada spermatogenesis dan sel sertoli testis kelinci ( oryctolagus cuniculus)
  11. Efisiensi reproduksi sapi peranakan ongole (po) dan persilangan limousin-po (limpo) hasil inseminasi buatan di kecamatan paciran kabupaten lamongan
  12. Pengaruh sari kulit dan buah semangka merah (citrullus lanatus) sebagai bahan pengencer terhadap motilitas dan viabilitas spermatozoa domba
  13. Pengaruh penambahan l-arginin dalam pengencer susu skim kuning telur terhadap motilitas dan viabilitas spermatozoa domba merino post thawing
  14. Efisiensi reproduksi sapi perah hasil inseminasi buatan di kecamatan sanankulon kabupaten blitar pada tahun 2015
  15. Efek protektif aluminium silikat terhadap kualitas spermatozoa, integrasi membran plasma dan gambaran histopatologis tubulus seminiferus yang diinduksi fusarium graminearum pada mencit jantan (mus musculus)
  16. Substitusi pakan isi rumen sapi sebagai alternatif perbaikan produktifitas ternak itik mojosari di desa kebonsari kecamatan candi sidoarjo