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Veterinaria Medika

ISSN 1979-1305

Vol. 5 / No. 3 / Published : 2012-11

TOC : 1, and page :157 - 162

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Original Article :

Decrease of spermatozoa fertility rate and overview histopathologic seminiferous tubules of mice (mus musculus) with malnutrition conditions

Author :

  1. Hernawati, Tatik*1
  2. Safitri, Erma*2
  3. Utama, Suzannita*3
  4. Mulyati, Sri*4
  1. Fakultas Kedokteran Hewan Universitas Airlangga
  2. Fakultas Kedokteran Hewan Universitas Airlangga
  3. Fakultas Kedokteran Hewan Universitas Airlangga
  4. Fakultas Kedokteran Hewan Universitas Airlangga

Abstract :

The research was conducted in addition aims to scientifically prove the decrease in fertility of sperm cells of male mice Mus musculus experiencing malnutrition conditions, as well as to demonstrate the histopathologic picture of the seminiferous tubules were damaged in mice Mus musculus male from malnutrition. The methods used are: Mus musculus male is experiencing malnutri ie fasted for 3 days onl ygiven to drink ad libitum compared with controls fed a normal fixed 300-400 grams per day per mice and drinking water ad libitum. We then test the fertility of sperm cells, sperm fertility rates obtained by bringing sperm and ovum cells in vitro is calculated based on the number of zygotes produced divided by the numberof ova multiplied by 100%. The histopathologic examination of the seminiferous tubules of the testis is doneby surgery and fabrication of histological preparations, and then observed microscopically at the damage occurs at 100 and 400 times. The results showed a significant difference between male mice created malnourished compared with controls, whereas in the treated mice showed a decrease in fertility malnutrition. Similarly, histopathologic observation of seminiferous tubules damage than the control. At the microscopic condition of malnutrition occurs in the seminiferous tubules swelling, bleeding and adhesin with the surrounding tissue and even degenerated tissue. 

Keyword :

Spermatozoa fertility rate, Histopathologic seminiferous tubules,

References :

  1. Alan R. and M.D.Gaby, (2000). Dehydroepiandrosterone. Biological Effects and Clinical Significance. (Abstr) . Melbourne : http://www.
  2. Abbas A.K., A.H.Lichtman and J.S. Pober, (2000). Congenital and acquired immunodeficiency disorder. In:Cellular and Molecular Immunology,4 th. United States : Ed,W.B Saunders.Co, 445-67.


Archive Article

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Volume : 5 / No. : 3 / Pub. : 2012-11
  1. Decrease of spermatozoa fertility rate and overview histopathologic seminiferous tubules of mice (mus musculus) with malnutrition conditions
  2. Antibacterial susceptibility of bacillus subtilis isolated from shrimp pond and fish pond sediment
  3. The efectivity of red rose flower(rosa damascena mill) extract as an antiseptic toward chronic stomatitis on phyton snake (python reticulatus)
  4. Potential rice bran fermented with enterobacter cloacae wpl 111 to the crude fiber disgestibility of broiler
  5. The decrease of progesterone-b receptor roles in abortion ewe by dexamethasone administration
  6. Antibiotic susceptibility pattern of staphylococcus aureus isolated from mastitis in dairy cattle at argopuro dairy cooperative in krucil probolinggo district
  7. Therapeutic effect of water extract leaf kedondong (lannea coromandelica) to levels of malondialdehyde (mda) and protease activity in ileum rat (rattus norvegicus) inflammatory bowel disease (ibd) induced by indomethacin
  8. The dynamic of maturation promoting factor (mpf) on cyprinus carpio oocytes after induced by artificial activation
  9. The role of d-alpha tocopherol therapy to blood glucose levels and levels of mda (malondialdehyde) in diabetes mellitus type 1 rats by mld-stz
  10. Oestrous decrease and ovarian histopathologic description of female mouse (mus musculus) with malnutrition condition
  11. Closed house method to influence of body weight, mortality rate and crop periode in broiler farm
  12. Insulin like growth factor-i complex sebagai alternatif antioksidan pada media pendewasaan spermatozoa kambing
  13. The effect of giving eugenia polyantha extract to liver histopathology on rattus norvegicus strain sprague dawley induced with dmba (dimetilbenz[a]antrasen)