UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 6 / No. 2 / Published : 2013-07

Order : 8, and page :115 - 120

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Original Article :

Effect of sambiloto (andrographis paniculata) extract based on histopathological changes of gouramy (osphronemus gouramy) villi intestine infected aeromonas hydrophila

Author :

  1. Fithriani, Dian*1
  2. Arimbi*2
  3. Sarudji, Suryani*3
  1. PPDH Fakultas Kedokteran Hewan Universitas Airlangga
  2. Fakultas Kedokteran Hewan Universitas Airlangga
  3. Fakultas Kedokteran Hewan Universitas Airlangga

Abstract :

The aim of this study was to know the effect of extract sambiloto leaf (Andrographis paniculata tohistopathological changes of Gouramy (Osphronemus gouramy) intestine which was infected by Aeromonas hydrophila. Twenty five gouramy with weight of 100 gram and 8-12 cm length were dividedinto five (n=5) groups, that were P0+, P1, P2, P3, and P4. Except P0+, the groups that infected with 106 CFU/mL of Aeromonas hydrophila in 5 L water, were dipped with 100 ppm sambiloto extract in thetime of 30, 60, 90, and 120 minutes respectively. The data of histopathological changes of intestinum were analyzed with Kruskal wallis test, then continued with Mann Whitney. This researched showed there were significant different (p<0.05) among groups based on histopathological changes of intestine. It was indicated that P4 (infected with Aeromonas hydrophila and dipping with sambiloto (Andrographis paniculata) in 120 minutes) was most effective dosage if be seen from histological changes was mildest.

Keyword :

Aeromonas hydrophila, Sambiloto (Andrographis paniculata) leaf extract, Intestine, Gouramy (Osphronemus gouramy), Dipping,


References :

Akbar, S.,(2011) Andrographis paniculata: A Review of Pharmacological Activities and Clinical Effect. Saudi Arabia : Medicinal Review. Department of Pharmaclogy Qassim University. Saudi Arabia. 16(1): 66-77.

Anggie, Safety Renny.,(2008) Studi Histopathologi Insang, Usus dan Otot Ikan Gurami (Osphronemus gouramy) akibat Infeksi Parasit Protozoa di Desa Carang Pulang Dramaga Bogor. Bogor : [Skripsi]. Fakultas Kedokteran Hewan Institut Pertanian Bogor.





Archive Article

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Volume : 6 / No. : 2 / Pub. : 2013-07
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  8. Effect Of Sambiloto (andrographis Paniculata) Extract Based On Histopathological Changes Of Gouramy (osphronemus Gouramy) Villi Intestine Infected Aeromonas Hydrophila
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