Catalog :




Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 7 / No. 1 / Published : 2014-02

TOC : 2, and page :7 - 16

Related with : Scholar   Yahoo!   Bing

Original Article :

Effect of infusum salam leaves (eugenia polyantha) on blood glucose level on the rat (rattus norwegicus) in alloxan induced

Author :

  1. Desak Ketut Sekar Cempaka Putri*1
  2. Bambang Hermanto*2
  3. Tjitra Wardani*3
  1. Mahasiswa Fakultas Kedokteran
  2. Dosen Fakultas Kedokteran
  3. Dosen Fakultas Kedokteran

Abstract :

This experiment is conducted in order to prove the theory that the infusum of bay leaf (Eugenia polyantha) may lower the blood glucose level of the sample rat which was afflicted with Diabetes Mellitus (DM). Twenty five rat samples (Rattus norwegicus) were divided into 5 groups, with each groups consisted of 5 rat samples. Those groups are: control group, using normal rats (not afflicted with DM) which were only given aquades of 1 ml/oral/samples, while 20 rat samples were afflicteddiabetesmelitus by injecting 200 mg/kg body weight of aloxanthrough intra peritoneal route. on the fifth day after the aloxan was administered, those rats became afflicted with DM, which is proven with the rise of the blood glucose level of >200mg/dl. The group which was given the treatment, the treatment 0 (P0) were the DM rats which were only given aquades 1ml/oral/day, treatment group 1 (P1) were the DM rats which were given 412.5 mg/150 g body weight/oral/day of bay leaves infusion, treatment group 2 (P2) were the DM rats which were given 825 mg/150 g body weight/oral/day of bay leaves infusion, and treatment group 3 (P3) were the DM rats which were given 1237.5 mg/150 g body weight/oral/day of bay leaves infusum. All samples were given the same method of treatment, by giving the dosage once daily for a period of 14 days. The observed parameter was theblood glucose level measurement from 0 hour, 1st hour, 2nd hour, 4th hour, 6th hour, 8th hour, day 7th, day 14th after the treatment was given. The data obtained was analysed using Anava. The result from giving the dosage of 825 mg/150 g body weight/oral/day of bay leaves infusion was the decrease in the blood glucose level of the rats on the 7th day, and the blood glucose level returned to normal on the 14th day, while giving the dosage of 1237.5 mg/150 g body weight/oral/day of bay leaves infusum resulted in the normalization of the blood glucose level on the 7th day, and the blood glucose dropped below normal on the 14th day.

Keyword :

Infusum, Eugenia polyantha leaf, Aloksan, Rats afflicted with DM, Blood glucose,


References :

  1. Dalimartha, (2004). Ramuan Tradisional untuk pengobatan diabetes mellitus. Jakarta : Ed. XI. Penebar Swadaya;73-94
  2. Meles, D.K, Wurlina dan Nian, (2009). Kadar glukosa darah setelah pemberian aloxan pada tikus putih (Rattus norwegicus). Surabaya : Veterinary journal. 5(4) : 34.
  3. Nugroho, A.E., (2006). Hewan Percobaan Diabetes Mellitus : Patologi dan Mekanisme Aksi Diabetogenik. . : Biodiversitas. 7(4) : 378-382


   


Archive Article

Cover Media Content

Volume : 7 / No. : 1 / Pub. : 2014-02
  1. Grant of ethanol extract of seeds papaya (carica papaya) in female rats (rattus novergicus) antifertilitas material, as an alternative to number and quality of egg cells
  2. Effect of infusum salam leaves (eugenia polyantha) on blood glucose level on the rat (rattus norwegicus) in alloxan induced
  3. Potential of phytase ezymes from rumen bacteria on sem analysis structural changes of rice bran as broiler feed
  4. The comparison of morphology between bovine oocyte vitrification before and after in vitro maturation
  5. The effect of exposing pregnant rat (rattus novergicus) to particulate matter on congenital disorder and resorption of embryos
  6. Ha gene phyloanalysis of influenza h1n1 2009 virus in surabaya
  7. Effect of seminal plasm of cow on goat’s spermatozoa plasma membran in milk diluter on semen freezhing
  8. Histopathological view pyramid cell on cerebrum of white rat (rattus norvegicus) were exposed with methylmercury which administrated with cdp-choline as neuroprotective agent
  9. Giving epigallocathechin gallate (egcg) toward the expression of estrogen receptor at female white mouse (rattus norvegicus)
  10. Human resource management goad farm of the cross breed etawa goat independent farm, farmer groups and businesses in the town of turi sleman regency
  11. The pattern of antimicrobial susceptibility of salmonella sp isolated from beef
  12. Potential mycotoxin binders on histopathology of the mammary gland experiencing neoplasia in pregnant mice (mus musculus) with exposed zearalenone
  13. Potential of mycotoxin binders on weight and length of fetus pregnant mice (mus musculus) with zearalenone exposure
  14. Prevalence of worm disease in cattle gastrointestinal peranakan ongole (po) and simental cattle in the subdistrict laren, district lamongan
  15. The giving of anti- toxoplasma gondii membran immunoglobulin y before infection reduce apoptotic index liver mice