Veterinaria Medika
ISSN 1979-1305
Vol. 10 / No. 1 / Published : 2017-02
Order : 10, and page :71 - 76
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Original Article :
Effect of mangosteen (garcinia mangostana linn.) pericarp extracts on the diameter of mice (mus musculus) pre antral and antral follicles
Author :
- Rachmadika Prihandanu Yuanizar*1
- Suzanita Utama*2
- Widjiati*3
- Mahasiswa Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
- Dosen Fakultas Kedokteran Hewan
Abstract :
This research aimed to investigate the effect of Mangosteen (Garcinia mangostanaLinn.) pericarp extract on diameter of mice (Mus musculus) pre antral and antral follicles.Twenty female mice were divided into five groups and treated for 12 days. C– administeredorally 0.5 ml NaCMC solution, C+ administered orally 0.26 ml/20g Microgynon®, T1,T2, and T3 administered orally 100, 200, and 300 mg/kg BW mangosteen (Garciniamangostana Linn.) pericarp extract. Experimental groups received the treatments for12 days, then animals of each groups were sacrificed by euthanasia using diethyl ether.Ovaries were dissected out for observation. The diameter of pre antral and antral follicleswere measured under microscope with 100x, 400x, and 1000x magnification and usingOpti Lab Viewer and Image Raster 3 application. ANOVA test did not show significantdifference (p>0.05) among treatment.
Keyword :
Garcinia mangostana Linn, Mus musculus, pre antral, antral, follicles,
References :
Hubler, M. and S. Arnlod.,(2000) Prevention of Pregnancy in Bithces with the Progesterone Antagonist Anlepristone (Alizone). . 142(7): 381-6. : Schweiz Arch Tierheilkd
Nurhuda, O. S., N. Suhana dan Sadikin.,(1995) Pengaruh Pemberian Buah Pare terhadap Jumlah dan Motilitas Spermatozoa Tikus Jantan Strain LMR. 3 (2) : 13-20 : Jurnal Kedokteran YARSI
Agustina, K., W. Sumali dan K. Dadang,(2005) Efek Estrogenik Biji Klebet (Trigonella foecum-graecum L.) terhadap Perkembangan Uterus Tikus Putih Betina 4 (2) : 280-285. : Jurnal Bahan Alam Indonesia
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