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Veterinaria Medika

ISSN 1979-1305

Vol. 10 / No. 1 / Published : 2017-02

TOC : 4, and page :23 - 30

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Original Article :

Effect of vitamin c and e towards histopathological changes of duodenum in mice induced with borax

Author :

  1. Rizki Amalia*1
  2. Wurlina*2
  3. Eka Pramyrtha Hestianah*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The aim of this research was to investigate the effect of vitamin C and E towardshistopathological changes of duodenum in mice induced with borax. Twenty five malemice of BALB/c strain divided into five groups; K1 (vitamin control) was given 0,56 mg/mice /day of vitamin C solution combinated 2,1 mg/mice/day of vitamin E solution, K2(borax control) was given 5,2 mg/mice/day of boraks, P1 was given combination of 0,56mg/mice/day vitamin C and 2,1 mg/mice/day vitamin E solutions and 5,2 mg/mice/ dayof borax, P2 was given combination of 1,12 mg/mice /day of vitamin C and 4,2 mg/mice/day of vitamin E solutions and 5,2 mg/mice/day of borax, P3 was given combinationof 2,24 mg/mice/day of vitamin C and 4,2 mg/mice/day of vitamin E solutions and 5,2mg/mice/day of borax. Borax solution on P3, P4 and P5 groups induced in an hour aftereach groups treated with combination of vitamin C and E solutions. The treatment weregiven by oral gavage for 14 days. The result against submucosal edema of duodenumindicated there was not any significant difference (P>0.05) between K1 (vitamin control)and K2 (boraks control) groups. There was a signifant difference between K2 (boraxcontrol) with P1 and P3 groups. There was indicated that vitamin C and E decrease thesubmucosal edema of duodenum induced with borax. The result against the damage ofmucous epithelial indicated there was a significant difference (P<0,05) between K2 groupwith P1, P2, and P3 groups. There was not any significant difference between P1, P2, andP3 groups. There was indicated that vitamin C and vitamin E could repair the submucosaledema of duodenum induced with boraks.

Keyword :

Vitamin E, vitamin C, submucosal edema, mucous epithelial, boraks,

References :

  1. Arimbi., A. Azmijah., R. Darsono., H. Plumeriastuti., T.V Widiyatno., D. Legowo, (2013). Buku Ajar Patologi Veteriner : Respon Sel dan Jaringan Terhadap Jejas serta Gangguan Hemodinamik. . 10-60 : Fakultas Kedokteran Hewan Universitas Airlangga. Surabaya.
  2. Alexander J. M., and Balz F., (2013). Myths, Artifacts, and Fatal Flaws: Identifying Limitations and Opportunities in Vitamin C Research. 1 : Nutrients Journal
  3. Bezabeh, M., A. Tesfaye, B. Ergicho, M. Erke, S. Mengistu, A. Bedane, A. Desta. , (2004). General Pathology : Lecture Notes For Health Science Students. Jimma University, Gondar University, Harayama University,. 68-69 : Dedub University. Ethiopia.


Archive Article

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Volume : 10 / No. : 1 / Pub. : 2017-02
  1. Isolation and identification vibrio sp as vibriosis cause of agent at grouper fish (epinephelus fuscoguttatus) in banyuwangi regency
  2. Identification of species and stage of mite causes scabies by crusting severity on the rabbits
  3. Potency of curcumin on histopathological changes in the kidney of pregnant mice (mus musculus) exposed to cadmium
  4. Effect of vitamin c and e towards histopathological changes of duodenum in mice induced with borax
  5. The effects of crude protein bovine seminal plasma addition in skim milk and egg yolk diluent to motility, viability, dna fragmentation, and necrosis of ram spermatozoa after equilibration
  6. The effect of red fruit oil (pandanus conoideus lam.) on histopathology of follicle development in infertile mice modelling
  7. Prevalence and infection level of gastrointestinal worm nematode on long tailed macaque (macaca fascicularis) at taman wisata wendit malang regency
  8. Prevalence of distomatosis on various type of slaughtered cattle at penggaron semarang abattoir
  9. Pattern of antibiotics resistance on escherichia coli that isolated from raw milk in surabaya
  10. Effect of mangosteen (garcinia mangostana linn.) pericarp extracts on the diameter of mice (mus musculus) pre antral and antral follicles
  11. Semen quality, hsp 70 expression and dna damage of post thawing limousine bull spermatozoa after cooled at 5 °c
  12. The effects of propolis on histological liver in male mice (mus musculus)
  13. Effect of rosella flower (hibiscus sabdariffa l.) extract on liver histhopathologic of male mice (mus musculus) exposed plumbum acetate
  14. Effect of electrical field on the death of staphylococcus aures in milk
  15. The effect of mimosa pudica root extract to histopathological representation of rattus norvegicus liver injected with naja sputatrix venom
  16. Androgen dihydrotestosterone and its role in male reproductive system