UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 7 / No. 1 / Published : 2014-02

Order : 1, and page :1 - 6

Related with : Scholar   Yahoo!   Bing

Original Article :

Grant of ethanol extract of seeds papaya (carica papaya) in female rats (rattus novergicus) antifertilitas material, as an alternative to number and quality of egg cells

Author :

  1. Yenny Puspitasari*1
  2. Byba Melda Suhita*2
  1. Nursing Faculty at STIKes Surya Mitra Husada
  2. Nursing Faculty at STIKes Surya Mitra Husada

Abstract :

Indonesia is a developing country with population density problem occupies the fourth rank of the world. One effort made to suppress the population growth is through family planning. One of the efforts to succeed family planning is the development of raw materials from papaya for antifertility natural ingredients. The purpose of this research was to study the effects of ethanol extract of papaya seeds on antifertility in female rats. The benefits of this research was to provide information about the use of ethanol extract of papaya seeds as antifertility in animals and make ethanol extract of papaya seeds as an alternative contraceptive drug. This study used post-test only control group design. Samples were taken in random. The independent variable was ethanol extract of papaya seeds in various doses. The dependent variables were folliculogenetic examination, increase infertility, decresed quality egg and fertilization number. Data analysis to determine the different mean number of follicles, increase infertility, decresed quality egg and fertilization number weer performed with one-way ANAVA test. Data analysis for the correlation between the levels of 17- estradiol in blood and the number of follicles in folliculogenetic process was performed using bivariate correlation test. Ethanol extract of papaya seeds in dose of 100 mg/kg, 200 mg/kg, 300 mg/kg lowered the number of tertiary and de Graaf follicles, while primary and secondary follicles did not decrease. The number of primary follicles are significantly different (p < 0,05). No difference in the number of eggs produced after treatment, indicating no difference in fertility after obtaining ethanol extract of papaya seeds, it is evident from the value of p = 0.000 α = 0.05. No difference in the number of mature eggs after IVF. It is shown from the value of p = 0.000 α = 0.05. No difference in fertilization rate. It is shown from the value of p = 0.000 α = 0.05. Ethanol extract of papaya seeds is increase infertility, decreased quality egg cells, to decrease the number of tertiary and de Graaf follicles in the ovary and decrease fertilization number, causing infertility in female rats.

Keyword :

Ethanol extract of papaya seeds, Folliculogenesis, Infertility, Eggs quality, Number fertilization,


References :

O.P Astirin, dan Muthmainah,(2002) Struktur Histologis Ovarium Tikus (Rattus novergicus) Gravid Setelah Pemberian Ekstrak Momordica Charantia L Jakarta : Jurnal Pharmacon., 26-30





Archive Article

Cover Media Content

Volume : 7 / No. : 1 / Pub. : 2014-02
  1. Grant Of Ethanol Extract Of Seeds Papaya (carica Papaya) In Female Rats (rattus Novergicus) Antifertilitas Material, As An Alternative To Number And Quality Of Egg Cells
  2. Effect Of Infusum Salam Leaves (eugenia Polyantha) On Blood Glucose Level On The Rat (rattus Norwegicus) In Alloxan Induced
  3. Potential Of Phytase Ezymes From Rumen Bacteria On Sem Analysis Structural Changes Of Rice Bran As Broiler Feed
  4. The Comparison Of Morphology Between Bovine Oocyte Vitrification Before And After In Vitro Maturation
  5. The Effect Of Exposing Pregnant Rat (rattus Novergicus) To Particulate Matter On Congenital Disorder And Resorption Of Embryos
  6. Ha Gene Phyloanalysis Of Influenza H1n1 2009 Virus In Surabaya
  7. Effect Of Seminal Plasm Of Cow On Goat’s Spermatozoa Plasma Membran In Milk Diluter On Semen Freezhing
  8. Histopathological View Pyramid Cell On Cerebrum Of White Rat (rattus Norvegicus) Were Exposed With Methylmercury Which Administrated With Cdp-choline As Neuroprotective Agent
  9. Giving Epigallocathechin Gallate (egcg) Toward The Expression Of Estrogen Receptor At Female White Mouse (rattus Norvegicus)
  10. Human Resource Management Goad Farm Of The Cross Breed Etawa Goat Independent Farm, Farmer Groups And Businesses In The Town Of Turi Sleman Regency
  11. The Pattern Of Antimicrobial Susceptibility Of Salmonella Sp Isolated From Beef
  12. Potential Mycotoxin Binders On Histopathology Of The Mammary Gland Experiencing Neoplasia In Pregnant Mice (mus Musculus) With Exposed Zearalenone
  13. Potential Of Mycotoxin Binders On Weight And Length Of Fetus Pregnant Mice (mus Musculus) With Zearalenone Exposure
  14. Prevalence Of Worm Disease In Cattle Gastrointestinal Peranakan Ongole (po) And Simental Cattle In The Subdistrict Laren, District Lamongan
  15. The Giving Of Anti- Toxoplasma Gondii Membran Immunoglobulin Y Before Infection Reduce Apoptotic Index Liver Mice

Information VETMED