Catalog :




Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 6 / No. 2 / Published : 2013-07

TOC : 11, and page :133 - 138

Related with : Scholar   Yahoo!   Bing

Original Article :

The effect of borax to duodenal histopathological changes in rats (rattus norvegicus)

Author :

  1. Purnama, M.T.E*1
  2. Widjaja, N.M.R*2
  3. Plumeriastuti, Hany*3
  1. PPDH Fakultas Kedokteran Hewan Universitas Airlangga
  2. Fakultas Kedokteran Hewan Universitas Airlangga
  3. Fakultas Kedokteran Hewan Universitas Airlangga

Abstract :

The purpose of this study was to evaluate the histopathological changes in duodenum of wistar rats after giving borax using different subchronic toxicity doses. The research has been done on April, 2 2012-May, 29th 2012 at Department of Veterinary Pathology , Faculty of Veterinary Medicine, University of Airlangga. Twenty male rats (Rattus norvegicus strain Wistar) aged 45 days with BW 100 g were used.These animals were divided into four groups (P0, P1, P2, and P3). P0 were treated with sterile aquadest0,5 ml/rats/day, P1 were treated with borax 19 mg/rats/day, P2 were treated with borax 26 mg/rats/day,and P3 were treated with borax 37 mg/rats/day. This research has been conducted for 14 days to determine the toxic effects of borax on the duodenum. The data were compared using Kruskal-Wallis testand Mann-Whitney test. Statistical comparisons were performed using SPSS v20.0 for windows. The result showed that borax significantly caused cloudy swelling, congestion, necrosis and erosion of the villi on duodenal histopathology (p<0,05).

Keyword :

Disodium tetraborate decahydrate, Duodenal histopathology, Borax,


References :

  1. Dieter, M.P., (1994). Toxicity and carcinogenicity studies of boric acid in male and female B6C3F1 mice.. . : Environ. Health Persp. 102(Suppl 7):93-97.
  2. Sugiyatmi, S. , (2006). nalisis Faktor-Faktor Risiko Pencemaran Bahan Toksik Boraks dan Pewarna pada Makanan Jajanan Tradisional yang Dijual Di Pasar-Pasar Kota Semarang Tahun 2006 . Semarang : [Tesis]. Program Pasca Sarjana Universitas Diponegoro. Semarang. 3-21.


   


Archive Article

Cover Media Content

Volume : 6 / No. : 2 / Pub. : 2013-07
  1. The influence of bacteriocin as a preservation of beef to extend storage at 4°c-
  2. Influence of infusa mangosteen peel (gracinia mangostana l) for blood glucose levels of hyperglycemic rats
  3. The potential of red roses extract (rosa damascena mill) as an antiseptic stomatitis in snakes (python reticulatus) on the total number leukocyte and defferential counting of leukocytes
  4. The effect of green bitter melon fruit flesh (momordica charantia l.) extract on mice (mus musculus) estrous cycle which superovulated with pmsg and hcg
  5. The antibiotica susceptibility of escherichia coli isolated from etawa goat milk
  6. Reproductive’s efficiency of madura cattle artificial insemination result at sumenep regency in 2012
  7. Digestibility value of proteinin formula feed for the cats (felis silvestris catus)
  8. Effect of sambiloto (andrographis paniculata) extract based on histopathological changes of gouramy (osphronemus gouramy) villi intestine infected aeromonas hydrophila
  9. Comparison of hemocytometer thoma and spectrophotometer method on sperm concentration examination of merino sheep semen
  10. Profil protein hemaglutinin (ha) berdasarkan berat molekul virus avian influenza isolat lokal
  11. The effect of borax to duodenal histopathological changes in rats (rattus norvegicus)
  12. Giving probiotics to increase milk production and milk proteins of dairy cattle in gresik randu padangan village
  13. Differential time of artificial insemination on the presentage regnancy of fat tailed sheep
  14. Pengaruh vaksinasi dengue multivalen terhadap ekspresi toll-like receptor dan sel t cd4+ pada kelinci ( white new zealand )
  15. Quality test of frozen semen of etawa goat-breed’s in three different kinds of extender with water incubator examination