UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 6 / No. 2 / Published : 2013-07

Order : 4, and page :97 - 102

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Original Article :

The effect of green bitter melon fruit flesh (momordica charantia l.) extract on mice (mus musculus) estrous cycle which superovulated with pmsg and hcg

Author :

  1. Agustina, G.A*1
  2. Mustofa, Imam*2
  3. Sunarso, Agus*3
  1. PPDH Fakultas Kedokteran Hewan Universitas Airlangga
  2. Fakultas Kedokteran Hewan Universitas Airlangga
  3. Fakultas Kedokteran Hewan Universitas Airlangga

Abstract :

This study aimed to determine the effect of bitter melon fruit flesh (Momordica charantia L.) extract onmice (Mus musculus) estrous cycle which superovulated with PMSG and hCG. Bitter melon fruit isknown to contain flavonoids and triterpenoids that are antigonadotropin. Thirty two head of mice were randomly divided into four groups, then superovulated by using 5 IU PMSG and 5 IU hCG intraperitoneally. The study used bitter melon fruit flesh exstract dosage 0 mg/g bw, 0.667 mg/g bw, 1.00mg/g bw, and 1.33 mg/g bw in 5% CMC respectively. Treatment carried 0.5 ml orally twice a day for tendays. Identification of estrous cycle conducted by examining vaginal smear administered four times aday, for ten days after treatment. The results of the study showed that the bitter melon fruit flesh extractwas not significantly (p>0.05) affect of proestrous and metestrous phase. All dose of bitter melon fruitflesh extract in this study was significantly extend (p<0,05) of estrous phase, meanwhile 1.00 mg/g bw and 1.33 mg/g bw dose of bitter melon fruit extract was significantly shorten (p>0,05) of diestrus phase.There were significantly extend (p<0,05) of mice treated with all dose of bitter melon fruit fleshcompared to nontreated mice. 

Keyword :

Mice, Bitter melon fruit, Estrous cycle,


References :

Rusmiati.,(2010) Pengaruh Ekstrak Metanol Kulit Kayu Durian (Durio zibethimus Murr) pada Struktur Mikroanatomi Ovarium dan Uterus Mencit (Mus musculus L.) Betina. Indonesia : Sains dan Terapan Kimia. 4(2):114.

Fitrianti, F.,(2001) ubungan Kadar Estradiol dan Progesteron dengan Panjang Siklus Estrus Tikus Putih (Rattus sp.) yang Disuperovulasi Bogor : [Skripsi]. Fakultas Kedokteran Hewan Institut Pertanian Bogor.





Archive Article

Cover Media Content

Volume : 6 / No. : 2 / Pub. : 2013-07
  1. The Influence Of Bacteriocin As A Preservation Of Beef To Extend Storage At 4°c-
  2. Influence Of Infusa Mangosteen Peel (gracinia Mangostana L) For Blood Glucose Levels Of Hyperglycemic Rats
  3. The Potential Of Red Roses Extract (rosa Damascena Mill) As An Antiseptic Stomatitis In Snakes (python Reticulatus) On The Total Number Leukocyte And Defferential Counting Of Leukocytes
  4. The Effect Of Green Bitter Melon Fruit Flesh (momordica Charantia L.) Extract On Mice (mus Musculus) Estrous Cycle Which Superovulated With Pmsg And Hcg
  5. The Antibiotica Susceptibility Of Escherichia Coli Isolated From Etawa Goat Milk
  6. Reproductive’s Efficiency Of Madura Cattle Artificial Insemination Result At Sumenep Regency In 2012
  7. Digestibility Value Of Proteinin Formula Feed For The Cats (felis Silvestris Catus)
  8. Effect Of Sambiloto (andrographis Paniculata) Extract Based On Histopathological Changes Of Gouramy (osphronemus Gouramy) Villi Intestine Infected Aeromonas Hydrophila
  9. Comparison Of Hemocytometer Thoma And Spectrophotometer Method On Sperm Concentration Examination Of Merino Sheep Semen
  10. Profil Protein Hemaglutinin (ha) Berdasarkan Berat Molekul Virus Avian Influenza Isolat Lokal
  11. The Effect Of Borax To Duodenal Histopathological Changes In Rats (rattus Norvegicus)
  12. Giving Probiotics To Increase Milk Production And Milk Proteins Of Dairy Cattle In Gresik Randu Padangan Village
  13. Differential Time Of Artificial Insemination On The Presentage Regnancy Of Fat Tailed Sheep
  14. Pengaruh Vaksinasi Dengue Multivalen Terhadap Ekspresi Toll-like Receptor Dan Sel T Cd4+ Pada Kelinci ( White New Zealand )
  15. Quality Test Of Frozen Semen Of Etawa Goat-breed’s In Three Different Kinds Of Extender With Water Incubator Examination

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